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anti-ABCC10 antibody :: Rabbit anti-Human ABCC10 Polyclonal Antibody

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Catalog # MBS9200760
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Product Name

ABCC10, Polyclonal Antibody

Also Known As

ABCC10 Antibody (Center)

Product Synonym Names
Multidrug resistance-associated protein 7; ATP-binding cassette sub-family C member 10; ABCC10; MRP7; SIMRP7
Antibody/Peptide Pairs
ABCC10 peptide (MBS9217444) is used for blocking the activity of ABCC10 antibody (MBS9200760)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
767-793
Immunogen Sequence Length
1492
OMIM
612509
3D Structure
ModBase 3D Structure for Q5T3U5
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Specificity
This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 amino acids from the Central region of human ABCC10.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ABCC10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCC10 antibody
The protein encoded by this gene is a member of the
superfamily of ATP-binding cassette (ABC) transporters. ABC
proteins transport various molecules across extra- and
intra-cellular membranes. ABC genes are divided into seven distinct
subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This
ABC full-transporter is a member of the MRP subfamily which is
involved in multi-drug resistance. Multiple transcript variants
encoding different isoforms have been found for this gene.
Applications Tested/Suitable for anti-ABCC10 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-ABCC10 antibody
WB~~1:1000

Western Blot (WB) of anti-ABCC10 antibody
ABCC10 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ABCC10 antibody detected the ABCC10 protein (arrow).
anti-ABCC10 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABCC10 antibody
ABCC10 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC10 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-ABCC10 antibody Immunohistochemistry (IHC) (IHC) image
Flow Cytometry (FC/FACS) of anti-ABCC10 antibody
ABCC10 Antibody (Center) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
anti-ABCC10 antibody Flow Cytometry (FC/FACS) (FC/FACS) image
NCBI/Uniprot data below describe general gene information for ABCC10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
161629
NCBI Official Full Name
multidrug resistance-associated protein 7 isoform MRP7
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
NCBI Official Symbol
ABCC10  [Similar Products]
NCBI Official Synonym Symbols
MRP7; SIMRP7; EST182763
  [Similar Products]
NCBI Protein Information
multidrug resistance-associated protein 7
UniProt Protein Name
Multidrug resistance-associated protein 7
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 10
Protein Family
UniProt Gene Name
ABCC10  [Similar Products]
UniProt Synonym Gene Names
MRP7; SIMRP7  [Similar Products]
UniProt Entry Name
MRP7_HUMAN
NCBI Summary for ABCC10
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
UniProt Comments for ABCC10
ABCC10: ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter; Transporter, ABC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: lysosomal membrane; integral to membrane; plasma membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP binding

Biological Process: metabolic process; transmembrane transport
Product References and Citations for anti-ABCC10 antibody
Kuang, Y.H., et al. Biochem. Pharmacol. 79(2):154-161(2010)
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Zhou, Y., et al. Biochem. Pharmacol. 77(6):993-1001(2009)
Hopper-Borge, E., et al. Cancer Res. 69(1):178-184(2009)
Shen, T., et al. PLoS ONE 4 (10), E7520 (2009) :

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-ABCC10 antibody
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