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anti-ABCG8 antibody :: Rabbit anti-Human ABCG8 Polyclonal Antibody

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Catalog # MBS851228
Unit / Price
  0.1 mg  /  $330 +1 FREE 8GB USB
Testing Data
Product Name

ABCG8, Polyclonal Antibody

Also Known As

ABCG8 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
673
OMIM
210250
3D Structure
ModBase 3D Structure for Q9H221
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified by protein A column containing 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.
Other Notes
Small volumes of anti-ABCG8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCG8 antibody
Rabbit polyclonal ABCG8(1) antibody was raised against a peptide corresponding to C terminal residues of human ABCG8.
Applications Tested/Suitable for anti-ABCG8 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-ABCG8 antibody
Peptide ELISA: 1:160,000
WB: 1:1,000-1:2,000

Testing Data of anti-ABCG8 antibody
anti-ABCG8 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for ABCG8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,592 Da
NCBI Official Full Name
ATP-binding cassette sub-family G member 8 isoform 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily G member 8
NCBI Official Symbol
ABCG8  [Similar Products]
NCBI Official Synonym Symbols
GBD4; STSL
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family G member 8
UniProt Protein Name
ATP-binding cassette sub-family G member 8
UniProt Synonym Protein Names
Sterolin-2
Protein Family
UniProt Gene Name
ABCG8  [Similar Products]
NCBI Summary for ABCG8
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCG8
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092). The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
Product References and Citations for anti-ABCG8 antibody
(1) Muller, M., Klein, I., Kopacsi, S., et al. Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity. FEBS Lett.2006; 580 (26): 6139-6144.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-ABCG8 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with ABCG8 and Muscle
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