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anti-ABO antibody :: Rabbit anti-Human ABO Polyclonal Antibody

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Catalog # MBS9201513
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ABO, Polyclonal Antibody

Also Known As

ABO Antibody (N-term)

Product Synonym Names
Histo-blood group ABO system transferase; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Histo-blood group A transferase; A transferase; Histo-blood group B transferase; B transferase; NAGAT; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; ABO
Product Gene Name
Antibody/Peptide Pairs
ABO peptide (MBS9223027) is used for blocking the activity of ABO antibody (MBS9201513)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
41-68
Immunogen Sequence Length
354
OMIM
110300
3D Structure
ModBase 3D Structure for P16442
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Specificity
This ABO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human ABO.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.34 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ABO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABO antibody
This gene encodes proteins related to the first discovered
blood group system, ABO. Which allele is present in an individual
determines the blood group. The 'O' blood group is caused by a
deletion of guanine-258 near the N-terminus of the protein which
results in a frameshift and translation of an almost entirely
different protein. Individuals with the A, B, and AB alleles
express glycosyltransferase activities that convert the H antigen
into the A or B antigen. Other minor alleles have been found for
this gene.
Product Categories/Family for anti-ABO antibody
Applications Tested/Suitable for anti-ABO antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ABO antibody
WB~~1:1000

Western Blot (WB) of anti-ABO antibody
ABO Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ABO antibody detected the ABO protein (arrow).
anti-ABO antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ABO. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40934
NCBI Official Full Name
histo-blood group ABO system transferase
NCBI Official Synonym Full Names
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
NCBI Official Symbol
NCBI Official Synonym Symbols
GTB; NAGAT; A3GALNT; A3GALT1
  [Similar Products]
NCBI Protein Information
histo-blood group ABO system transferase
UniProt Protein Name
Histo-blood group ABO system transferase
UniProt Synonym Protein Names
Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase (EC:2.4.1.40); Glycoprotein-fucosylgalactoside alpha-galactosyltransferase (EC:2.4.1.37); Histo-blood group A transferase; A transferase
UniProt Gene Name
UniProt Synonym Gene Names
A transferase; B transferase  [Similar Products]
UniProt Entry Name
BGAT_HUMAN
NCBI Summary for ABO
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ABO
ABO: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Belongs to the glycosyltransferase 6 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.1.37; Membrane protein, integral; EC 2.4.1.40; Transferase

Chromosomal Location of Human Ortholog: 9q34.2

Cellular Component: extracellular region; integral to membrane

Molecular Function: metal ion binding; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity; fucosylgalactoside 3-alpha-galactosyltransferase activity

Biological Process: protein amino acid glycosylation

Disease: Blood Group, Abo System
Product References and Citations for anti-ABO antibody
Thuresson, B., et al. Transfusion 48(3):493-504(2008)
Seltsam, A., et al. Transfusion 47(12):2330-2335(2007)
Twu, Y.C., et al. Transfusion 46(11):1988-1996(2006)
Jenkins, P.V., et al. Transfusion 46(10):1836-1844(2006)
Roubinet, F., et al. Transfusion 44(5):707-715(2004)

Precautions
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Disclaimer
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