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anti-ABRA antibody :: Rabbit anti-Human ABRA Polyclonal Antibody

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Catalog # MBS9208483
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Product Name

ABRA, Polyclonal Antibody

Also Known As

ABRA Antibody (C-term)

Product Synonym Names
Actin-binding Rho-activating protein; Striated muscle activator of Rho-dependent signaling; STARS; ABRA {ECO:0000312|EMBL:AAI051061}
Antibody/Peptide Pairs
ABRA peptide (MBS9219436) is used for blocking the activity of ABRA antibody (MBS9208483)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
Immunogen Sequence Length
3D Structure
ModBase 3D Structure for Q8N0Z2
Rabbit Ig
Species Reactivity
This ABRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-304 amino acids from the C-terminal region of human ABRA.
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ABRA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABRA antibody
ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity).
Applications Tested/Suitable for anti-ABRA antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ABRA antibody

Western Blot (WB) of anti-ABRA antibody
ABRA Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the ABRA antibody detected the ABRA protein (arrow).
anti-ABRA antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABRA antibody
ABRA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABRA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-ABRA antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ABRA. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
actin-binding Rho-activating protein
NCBI Official Synonym Full Names
actin binding Rho activating protein
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
actin-binding Rho-activating protein
UniProt Protein Name
Actin-binding Rho-activating protein
UniProt Synonym Protein Names
Striated muscle activator of Rho-dependent signaling; STARS
UniProt Gene Name
UniProt Synonym Gene Names
STARS  [Similar Products]
UniProt Entry Name
UniProt Comments for ABRA
ABRA: Acts as an activator of serum response factor (SRF)- dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.

Protein type: Transcription, coactivator/corepressor; Contractile; Actin-binding

Chromosomal Location of Human Ortholog: 8q23.1

Cellular Component: sarcomere; plasma membrane; actin cytoskeleton

Molecular Function: transcription coactivator activity; actin binding

Biological Process: transcription, DNA-dependent; protein import into nucleus, translocation; positive regulation of Rho protein signal transduction; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter
Product References and Citations for anti-ABRA antibody
Lamon, S., et al. J. Physiol. (Lond.) 587 (PT 8), 1795-1803 (2009) : Kuwahara, K., et al. J. Clin. Invest. 117(5):1324-1334(2007) Kuwahara, K., et al. Mol. Cell. Biol. 25(8):3173-3181(2005) Arai, A., et al. J. Biol. Chem. 277(27):24453-24459(2002) Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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