• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ACAA1 antibody :: Rabbit anti-Human ACAA1 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9205476
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ACAA1, Polyclonal Antibody

Also Known As

ACAA1 Antibody (Center)

Product Synonym Names
3-ketoacyl-CoA thiolase; peroxisomal; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase; ACAA1; ACAA; PTHIO
Antibody/Peptide Pairs
ACAA1 peptide (MBS9228708) is used for blocking the activity of ACAA1 antibody (MBS9205476)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
147-176
Immunogen Sequence Length
331
OMIM
604054
3D Structure
ModBase 3D Structure for P09110
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Specificity
This ACAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of human ACAA1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ACAA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACAA1 antibody
This gene encodes an enzyme operative in the
beta-oxidation system of the peroxisomes. Deficiency of this enzyme
leads to pseudo-Zellweger syndrome. Alternative splicing results in
multiple transcript variants.
Applications Tested/Suitable for anti-ACAA1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ACAA1 antibody
WB~~1:1000

Western Blot (WB) of anti-ACAA1 antibody
ACAA1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ACAA1 antibody detected the ACAA1 protein (arrow).
anti-ACAA1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ACAA1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44292
NCBI Official Full Name
3-ketoacyl-CoA thiolase, peroxisomal isoform b
NCBI Official Synonym Full Names
acetyl-CoA acyltransferase 1
NCBI Official Symbol
ACAA1  [Similar Products]
NCBI Official Synonym Symbols
ACAA; THIO; PTHIO
  [Similar Products]
NCBI Protein Information
3-ketoacyl-CoA thiolase, peroxisomal
UniProt Protein Name
3-ketoacyl-CoA thiolase, peroxisomal
UniProt Synonym Protein Names
Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase
UniProt Gene Name
ACAA1  [Similar Products]
UniProt Synonym Gene Names
ACAA; PTHIO  [Similar Products]
UniProt Entry Name
THIK_HUMAN
NCBI Summary for ACAA1
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for ACAA1
ACAA1: an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Protein type: Lipid Metabolism - fatty acid; EC 2.3.1.16; Lipid Metabolism - unsaturated fatty acid biosynthesis; Acetyltransferase; Amino Acid Metabolism - valine, leucine and isoleucine degradation

Chromosomal Location of Human Ortholog: 3p22.2

Cellular Component: peroxisomal matrix; intracellular membrane-bound organelle; membrane; peroxisome

Molecular Function: palmitoyl-CoA oxidase activity; protein binding; acetyl-CoA C-acyltransferase activity

Biological Process: fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid beta-oxidation; very-long-chain fatty acid metabolic process; bile acid metabolic process; unsaturated fatty acid metabolic process; cellular lipid metabolic process

Disease: D-bifunctional Protein Deficiency
Product References and Citations for anti-ACAA1 antibody
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000