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anti-ADAM33 antibody :: Rabbit anti-Human ADAM33 Polyclonal Antibody

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Catalog # MBS1493738
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

ADAM33, Polyclonal Antibody

Popular Item
Also Known As

ADAM33 Antibody

Product Synonym Names
ADAM 33; ADAM33; C20orf153
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
812
OMIM
600807
3D Structure
ModBase 3D Structure for Q9BZ11
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Disintegrin and metalloproteinase domain-containing protein 33 protein (140-420aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23387 / sc-23386
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ADAM33 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADAM33 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ADAM33 antibody
Recommended dilution: IHC:1:20-1:200

Immunohistochemistry (IHC) of anti-ADAM33 antibody
Immunohistochemistry of paraffin-embedded human lung tissue using MBS1493738 at dilution 1:100
anti-ADAM33 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ADAM33 antibody
Immunohistochemistry of paraffin-embedded human placenta tissue using MBS1493738 at dilution 1:100
anti-ADAM33 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ADAM33. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,554 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 33 isoform gamma preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 33
NCBI Official Symbol
ADAM33  [Similar Products]
NCBI Official Synonym Symbols
C20orf153; DJ964F7.1
  [Similar Products]
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 33
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 33
UniProt Gene Name
ADAM33  [Similar Products]
UniProt Synonym Gene Names
C20orf153; ADAM 33  [Similar Products]
UniProt Entry Name
ADA33_HUMAN
NCBI Summary for ADAM33
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
UniProt Comments for ADAM33
ADAM33: Genetic variations in ADAM33 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Protease; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: integral to membrane

Molecular Function: metalloendopeptidase activity; protein binding; zinc ion binding

Biological Process: proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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