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anti-ADCY1 antibody :: Rabbit anti-Human Adenylate Cyclase 1 Polyclonal Antibody

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Catalog # MBS2027382 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
Scan QR to view Datasheet
  0.01 mg  /  $105 +1 FREE 8GB USB
  0.02 mg  /  $125 +1 FREE 8GB USB
  0.05 mg  /  $170 +1 FREE 8GB USB
  0.1 mg  /  $220 +1 FREE 8GB USB
  0.2 mg  /  $320 +1 FREE 8GB USB
  1 mg  /  $760 +1 FREE 8GB USB
Product Name

Adenylate Cyclase 1 (ADCY1), Polyclonal Antibody

Full Product Name

Polyclonal Antibody to Adenylate Cyclase 1, Brain (ADCY1)

Matching Pairs
Matching Pairs
Unconjugated Antibody: Adenylate Cyclase 1 (MBS2027382)
APC-CY7 Conjugated Antibody: Adenylate Cyclase 1 (ADCY1) (MBS2054162)
Matching Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RILFNL LPAHVAQHFL MSNPRNMDLY YQSYSQVGVM FASIPNFNDF YIELDGNNMG VECLRLLNEI IADFDELMEK DFYKDIEKIK TIGSTYMAAV GLAPTSGTKA KKSISSHLST LADFAIEMFD VLDEINYQSY NDFVLRVGIN VGPVVAGVIG ARRPQYDIWG NTVNVASRMD STGVQGRIQV TEEVHRLLRR
OMIM
AC069008 Genomic DNA
3D Structure
ModBase 3D Structure for Q08828
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody is a rabbit polyclonal antibody raised against ADCY1. It has beenselected for its ability to recognize ADCY1 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
200ug/ml (lot specific)
Fragment
ADCY1 (Arg835~Asn1061)
Organism Species
Homo sapiens (Human)
Conjugate
No Conjugate
Immunogen
Recombinant ADCY1 (Arg835~Asn1061) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2054164
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-ADCY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADCY1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-ADCY1 antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-ADCY1 antibody
Western Blot: Sample: Recombinant ADCY1, Human.
anti-ADCY1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ADCY1 antibody
DAB staining on fromalin fixed paraffin-embedded Adrenal tissue)
anti-ADCY1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ADCY1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
123,440 Da
NCBI Official Full Name
adenylate cyclase type 1 isoform 1
NCBI Official Synonym Full Names
adenylate cyclase 1
NCBI Official Symbol
ADCY1  [Similar Products]
NCBI Official Synonym Symbols
AC1; DFNB44
  [Similar Products]
NCBI Protein Information
adenylate cyclase type 1
UniProt Protein Name
Adenylate cyclase type 1
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
Protein Family
UniProt Gene Name
ADCY1  [Similar Products]
NCBI Summary for ADCY1
This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for ADCY1
ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: cytoplasm; extracellular exosome; guanylate cyclase complex, soluble; integral component of plasma membrane; membrane raft; nucleus; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding; guanylate cyclase activity; metal ion binding

Biological Process: activation of protein kinase A activity; adenylate cyclase activation; adenylate cyclase-activating G-protein coupled receptor signaling pathway; axonogenesis; cAMP biosynthetic process; cAMP-mediated signaling; cellular response to calcium ion; cellular response to forskolin; cellular response to glucagon stimulus; cGMP biosynthetic process; circadian rhythm; G-protein coupled receptor signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; long-term memory; regulation of circadian rhythm; renal water homeostasis; response to drug; response to lithium ion; signal transduction

Disease: Deafness, Autosomal Recessive 44
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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