NP_001095940.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,831 Da
NCBI Official Full Name
alcohol dehydrogenase 6 isoform 1
NCBI Official Synonym Full Names
alcohol dehydrogenase 6 (class V)
NCBI Official Synonym Symbols
NCBI Protein Information
alcohol dehydrogenase 6; aldehyde reductase
UniProt Protein Name
Alcohol dehydrogenase 6
UniProt Entry Name
ADH6_HUMAN
NCBI Summary for ADH6
This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ADH6
ADH6: class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein type: Lipid Metabolism - fatty acid; EC 1.1.1.1; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - tyrosine
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: cytosol
Molecular Function: zinc ion binding; alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; ethanol binding
Biological Process: response to ethanol; xenobiotic metabolic process; ethanol oxidation
Research Articles on ADH6
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Products associated with anti-ADH6 antibody
Pathways associated with anti-ADH6 antibody
Diseases associated with anti-ADH6 antibody
Organs/Tissues associated with anti-ADH6 antibody
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