• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-AKR1C3 antibody :: Rabbit anti-Human AKR1C3 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS853775
Unit / Price
Scan QR to view Datasheet
  0.1 mg  /  $330 +1 FREE 8GB USB
Product Name

AKR1C3, Polyclonal Antibody

Full Product Name

AKR1C3 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
603966
3D Structure
ModBase 3D Structure for P42330
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified by peptide affinity column containing 2% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-AKR1C3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AKR1C3 antibody
Rabbit polyclonal AKR1C3 (1) antibody was raised against a 15 amino acid peptide corresponding to the C terminal residues of human AKR1C3 protein.
Applications Tested/Suitable for anti-AKR1C3 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
Application Notes for anti-AKR1C3 antibody
Peptide ELISA: 1:10,000-1:40,000
WB: 1:500-1:1,000
IF: 1:50-1:200
IHC: 1:100-1:500

Testing Data of anti-AKR1C3 antibody
anti-AKR1C3 antibody Testing Data image
Testing Data of anti-AKR1C3 antibody
anti-AKR1C3 antibody Testing Data image
Testing Data of anti-AKR1C3 antibody
anti-AKR1C3 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for AKR1C3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,364 Da
NCBI Official Full Name
aldo-keto reductase family 1 member C3 isoform 2
NCBI Official Synonym Full Names
aldo-keto reductase family 1 member C3
NCBI Official Symbol
AKR1C3  [Similar Products]
NCBI Official Synonym Symbols
DD3; DDX; PGFS; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS
  [Similar Products]
NCBI Protein Information
aldo-keto reductase family 1 member C3
UniProt Protein Name
Aldo-keto reductase family 1 member C3
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2 (EC:1.1.1.357
UniProt Gene Name
AKR1C3  [Similar Products]
UniProt Synonym Gene Names
DDH1; HSD17B5; KIAA0119; PGFS; PGFS  [Similar Products]
NCBI Summary for AKR1C3
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
UniProt Comments for AKR1C3
Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000