NP_000889.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
amine oxidase
NCBI Official Synonym Full Names
monoamine oxidase B
NCBI Protein Information
amine oxidase [flavin-containing] B
UniProt Protein Name
Amine oxidase [flavin-containing] B
UniProt Synonym Protein Names
Monoamine oxidase type B; MAO-B
UniProt Synonym Gene Names
UniProt Entry Name
AOFB_HUMAN
NCBI Summary for MAOB
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]
UniProt Comments for MAOB
MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family.
Protein type: Membrane protein, integral; Amino Acid Metabolism - histidine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - glycine, serine and threonine; Oxidoreductase; Amino Acid Metabolism - tyrosine; Mitochondrial; Amino Acid Metabolism - arginine and proline; EC 1.4.3.4; Amino Acid Metabolism - tryptophan
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: integral to membrane; mitochondrial envelope; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion
Molecular Function: amine oxidase activity; electron carrier activity; FAD binding; protein homodimerization activity
Biological Process: dopamine catabolic process; hydrogen peroxide biosynthetic process; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to aluminum ion; response to corticosterone stimulus; response to drug; response to ethanol; response to lipopolysaccharide; response to selenium ion; response to toxin; substantia nigra development; xenobiotic metabolic process
Research Articles on MAOB
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Products associated with anti-MAOB antibody
Pathways associated with anti-MAOB antibody
Diseases associated with anti-MAOB antibody
Organs/Tissues associated with anti-MAOB antibody
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