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anti-ARHGDIG antibody :: Rabbit anti-Human ARHGDIG Polyclonal Antibody

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Catalog # MBS9605878
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

ARHGDIG, Polyclonal Antibody

Popular Item
Also Known As

ARHGDIG Antibody

Product Synonym Names
Arhgdig; GDIR3_HUMAN; OTTHUMP00000067353; OTTHUMP00000194914; Rho GDI 3; Rho GDI gamma; Rho GDP dissociation inhibitor (GDI) gamma; Rho GDP dissociation inhibitor 3; Rho GDP dissociation inhibitor gamma; Rho GDP-dissociation inhibitor 3; Rho-GDI gamma; RHOGDI 3; RhoGDI gamma; RHOGDI3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
225
3D Structure
ModBase 3D Structure for Q99819
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
ARHGDIG antibody detects endogenous levels of total ARHGDIG
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide
Subcellular Location
Cytoplasm.
Tissue Specificity
Primarily expressed in pancreas and brain.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-ARHGDIG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ARHGDIG antibody
Function: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP-and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
Similarity: Belongs to the Rho GDI family.
Applications Tested/Suitable for anti-ARHGDIG antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
Application Notes for anti-ARHGDIG antibody
WB: 1:500-1:1000
IF/ICC: 1:100-1:500

Western Blot (WB) of anti-ARHGDIG antibody
Western blot analysis of extracts from A549/Jurkat cells, using ARHGDIG antibody.
anti-ARHGDIG antibody Western Blot (WB) (WB) image
Immunofluorescene (IF) of anti-ARHGDIG antibody
MBS9605878 staining A549 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
anti-ARHGDIG antibody Immunofluorescene (IF) image
NCBI/Uniprot data below describe general gene information for ARHGDIG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 25 kD
Predicted: 26 kDa
NCBI Official Full Name
rho GDP-dissociation inhibitor 3
NCBI Official Synonym Full Names
Rho GDP dissociation inhibitor gamma
NCBI Official Symbol
ARHGDIG  [Similar Products]
NCBI Official Synonym Symbols
RHOGDI-3
  [Similar Products]
NCBI Protein Information
rho GDP-dissociation inhibitor 3
UniProt Protein Name
Rho GDP-dissociation inhibitor 3
UniProt Synonym Protein Names
Rho-GDI gamma
UniProt Gene Name
ARHGDIG  [Similar Products]
UniProt Synonym Gene Names
Rho GDI 3  [Similar Products]
NCBI Summary for ARHGDIG
The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010]
UniProt Comments for ARHGDIG
Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-ARHGDIG antibody
Organs/Tissues associated with anti-ARHGDIG antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with ARHGDIG and Brain
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