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Rabbit anti-Human b-Amyloid 1-40, 42 Polyclonal Antibody

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Catalog # MBS613519
Unit / Price
  0.1 mL  /  $720 +1 FREE 8GB USB
anti-b-Amyloid 1-40, 42 antibody
Product Name

b-Amyloid 1-40, 42, Polyclonal Antibody

Also Known As

b-Amyloid 1-40, 42

Product Synonym Names
Anti -b-Amyloid 1-40, 42
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Recognizes human b-amyloid 1-40 and b-amyloid 1-42. The peptide sequence has high degree of homology with mouse b-amyloid 1-40 and b-amyloid 1-42. Weak crossreactivity is observed with b-amyloid 1-28 and b-amyloid 12-28. No crossreactivity is observed with CGRP.
Purity/Purification
Serum
Serum
Form/Format
Supplied as a liquid in PBS containing 0.05% sodium azide
Immunogen
Synthetic b-amyloid 1-40 conjugated to BSA
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-b-Amyloid 1-40, 42 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-b-Amyloid 1-40, 42 antibody
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. One of the most important and initial step involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43 aa peptides (beta amyloid1-40, 1-42, and 1-43). Polymerization of b-amyloid (Ab) and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition. Ab deposits have also been found to contain 2 additional proteins termed a-synuclein and b-synuclein. The 140 aa a-synucleins is identical with non- Ab component (NACP) of AD. The 134 aa human b-synuclein is homologous to 14kD bovine phosphoneuroprotein 14. Mutations in a-synuclein gene causing a replacement of alanine with a threonine may cause the protein to misfold. Synucleins are primarily expressed in the brain. At least 3 forms: two large (140 aa SYN-1 & 149 aa SYN-2) and a small form (SYN-3, 42 aa) are produced by alternative splicing.

Rabbit anti-human beta Amyloid antibodies was raised using synthetic b-amyloid conjugated to BSA. Full-length b-amyloid 1-40 control immunogenic peptide is also available to confirm specificity of antibodies (A2275-75G).
Applications Tested/Suitable for anti-b-Amyloid 1-40, 42 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-b-Amyloid 1-40, 42 antibody
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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