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anti-BAG2 antibody :: Rabbit anti-Human BAG family molecular chaperone regulator 2 Polyclonal Antibody

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Catalog # MBS1492793
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

BAG family molecular chaperone regulator 2 (BAG2), Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human BAG family molecular chaperone regulator 2 polyclonal Antibody(BAG2)

Product Synonym Names
BAG-2; Bcl-2-associated athanogene 2; BAG2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
211
OMIM
603882
3D Structure
ModBase 3D Structure for O95816
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human BAG family molecular chaperone regulator 2 protein (1-211aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68948 / sc-68949
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-BAG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BAG2 antibody
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
Applications Tested/Suitable for anti-BAG2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-BAG2 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-BAG2 antibody
All lanes: BAG family molecular chaperone regulator 2 antibody at 6ug/ml
Lane 1:Jurkat whole cell lysate
Lane 2:Hela whole cell lysate
Lane 3:HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 24,21 kDa
Observed band size: 24 kDa

anti-BAG2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-BAG2 antibody
Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS1492793 at dilution 1:100
anti-BAG2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-BAG2 antibody
Immunohistochemistry of paraffin-embedded human kidney using MBS1492793 at dilution 1:100
anti-BAG2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for BAG2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,189 Da
NCBI Official Full Name
BAG family molecular chaperone regulator 2
NCBI Official Synonym Full Names
BCL2 associated athanogene 2
NCBI Official Symbol
NCBI Official Synonym Symbols
BAG-2; dJ417I1.2
  [Similar Products]
NCBI Protein Information
BAG family molecular chaperone regulator 2
UniProt Protein Name
BAG family molecular chaperone regulator 2
UniProt Synonym Protein Names
Bcl-2-associated athanogene 2
UniProt Gene Name
UniProt Synonym Gene Names
BAG-2  [Similar Products]
UniProt Entry Name
BAG2_HUMAN
NCBI Summary for BAG2
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
UniProt Comments for BAG2
BAG2: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 6p12.1-p11.2

Cellular Component: cytosol

Molecular Function: chaperone binding; identical protein binding; protein binding

Biological Process: protein folding; protein metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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