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anti-BATF3 antibody :: Rabbit anti-Human BATF3 Polyclonal Antibody

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Catalog # MBS153454
Unit / Price
  0.1 mg  /  $375 +1 FREE 8GB USB
Product Name

BATF3, Polyclonal Antibody

Popular Item
Also Known As

BATF3 Antibody

Product Synonym Names
Basic leucine zipper transcriptional factor ATF-like 3; SNFT; JDP1; JUNDM1; basic leucine zipper transcription factor, ATF-like 3
Antibody/Peptide Pairs
BATF3 peptide (MBS153953) is used for blocking the activity of BATF3 antibody (MBS153454)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
127
OMIM
612470
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
BATF3 antibody is human, mouse and rat reactive. BATF3 antibody is predicted to have no cross-reactivity to other BATF family members.
Purity/Purification
BATF3 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (lot specific)
Conjugate
Unconjugated
Immunogen
BATF3 antibody was raised against a 16 amino acid peptide near the amino terminus of human BATF3.
Buffer
BATF3 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
BATF3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Other Notes
Small volumes of anti-BATF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BATF3 antibody
BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun (1) and can repress the transcription of IL-2 and MMP-1 (1,2). BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells (3,4).
Applications Tested/Suitable for anti-BATF3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-BATF3 antibody
BATF3 body can be used for detection of BATF3 by Western blot at 1 - 2 ug/ml.

Optimal dilutions for each application to be determined by the researcher.

Western Blot (WB) of anti-BATF3 antibody
Western blot analysis of BATF3 in 293 cell lysate with BATF3 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
anti-BATF3 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for BATF3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Related Accession #
Molecular Weight
Predicted: 14 kDa

Observed: 17 kDa
NCBI Official Full Name
basic leucine zipper transcriptional factor ATF-like 3
NCBI Official Synonym Full Names
basic leucine zipper transcription factor, ATF-like 3
NCBI Official Symbol
BATF3  [Similar Products]
NCBI Official Synonym Symbols
JDP1; SNFT; JUNDM1
  [Similar Products]
NCBI Protein Information
basic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; Jun dimerization protein 1; Jun dimerization protein p21SNFT; 21-kD small nuclear factor isolated from T cells; 21 kDa small nuclear factor isolated from T-cells
UniProt Protein Name
Basic leucine zipper transcriptional factor ATF-like 3
UniProt Synonym Protein Names
21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT
UniProt Gene Name
BATF3  [Similar Products]
UniProt Synonym Gene Names
SNFT; B-ATF-3  [Similar Products]
UniProt Entry Name
BATF3_HUMAN
NCBI Summary for BATF3
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
UniProt Comments for BATF3
BATF3: Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12- O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities. Belongs to the bZIP family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q32.3

Cellular Component: nucleus

Molecular Function: transcription corepressor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; response to virus; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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