• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-BGLAP antibody :: Rabbit anti-Human BGLAP Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9127293
Unit / Price
Scan QR to view Datasheet
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Product Name

BGLAP, Polyclonal Antibody

Full Product Name

BGLAP

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
112260
3D Structure
ModBase 3D Structure for P02818
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Species
Human
Immunogen
Recombinant Protein
Other Notes
Small volumes of anti-BGLAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-BGLAP antibody
Applications Tested/Suitable for anti-BGLAP antibody
Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-BGLAP antibody
Immunohistochemistry of paraffin-embedded mouse stomach using BGLAP antibody at dilution of 1:100 (40x lens).
anti-BGLAP antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-BGLAP antibody
Immunohistochemistry of paraffin-embedded human stomach using BGLAP antibody at dilution of 1:100 (40x lens).
anti-BGLAP antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-BGLAP antibody
Immunohistochemistry of paraffin-embedded mouse lung using BGLAP antibody at dilution of 1:100 (40x lens).
anti-BGLAP antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for BGLAP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
100
NCBI Official Full Name
Osteocalcin
NCBI Official Synonym Full Names
bone gamma-carboxyglutamate (gla) protein
NCBI Official Symbol
BGLAP  [Similar Products]
NCBI Official Synonym Symbols
OC; BGP; OCN
  [Similar Products]
NCBI Protein Information
osteocalcin; bone Gla protein; gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin)
UniProt Protein Name
Osteocalcin
UniProt Synonym Protein Names
Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
Protein Family
UniProt Gene Name
BGLAP  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
OSTCN_HUMAN
NCBI Summary for BGLAP
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
UniProt Comments for BGLAP
osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family.

Protein type: Secreted, signal peptide; Cell development/differentiation; Secreted

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: Golgi apparatus; extracellular space; rough endoplasmic reticulum; cytoplasm; dendrite; perikaryon

Molecular Function: structural constituent of bone; hydroxyapatite binding; calcium ion binding; structural molecule activity

Biological Process: response to drug; response to gravity; regulation of bone resorption; response to glucocorticoid stimulus; cell aging; response to testosterone stimulus; bone mineralization; osteoblast development; odontogenesis; osteoblast differentiation; response to vitamin D; response to ethanol; regulation of osteoclast differentiation; response to vitamin K; response to estrogen stimulus; response to zinc ion; response to mechanical stimulus; response to hydroxyisoflavone; response to activity; cell adhesion; skeletal development; regulation of bone mineralization
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000