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anti-BIGM103 antibody :: Rabbit anti-Human BIGM103 Polyclonal Antibody

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Catalog # MBS9608321
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

BIGM103, Polyclonal Antibody

Popular Item
Also Known As

BIGM103 Antibody

Product Synonym Names
4933419D20Rik; AA986696; BCG induced integral membrane protein 103; BCG induced integral membrane protein BIGMo-103 (Up-regulated by BCG-CWS) (Hypothetical protein); LIV-1 subfamily of ZIP zinc transporter 6; LZT Hs6; MGC108852; PP3105; SLC39A8; Solute carrier family 39 (zinc transporter), member 8 (SLC39A8); Solute carrier family 39 (zinc transporter), member 8; Solute carrier family 39 member 8; zinc transporter ZIP8; ZIP8; Zrt-and Irt-like protein 8
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
460
3D Structure
ModBase 3D Structure for Q9C0K1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
BIGM103 antibody detects endogenous levels of total BIGM103
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human BIGM103
Subcellular Location
Membrane; Multipass Membrane Protein
Tissue Specificity
Expressed in thymus, placenta, lung, liver, pancreas and, to a lower extent, in spleen, testis, ovary, small intestine, colon, leukocyte, heart. Highest expression is observed in pancreas.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-BIGM103 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BIGM103 antibody
Function: Acts as a manganese and zinc influx transporter (PubMed:12504855, PubMed:26637978). Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain (PubMed:26637978).
Similarity: Belongs to the ZIP transporter (TC 2.A.5) family.
Applications Tested/Suitable for anti-BIGM103 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-BIGM103 antibody
WB: 1:1000-3000
IHC: 1:200

Immunohistochemistry (IHC) of anti-BIGM103 antibody
MBS9608321 at 1/100 staining Human Head and neck cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-BIGM103 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-BIGM103 antibody
Western blot analysis of BIGM103 using LOVO whole lysates.
anti-BIGM103 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for BIGM103. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 50 kDa
Predicted: 50 kDa
NCBI Official Full Name
zinc transporter ZIP8 isoform a
NCBI Official Synonym Full Names
solute carrier family 39 member 8
NCBI Official Symbol
SLC39A8  [Similar Products]
NCBI Official Synonym Symbols
ZIP8; CDG2N; PP3105; BIGM103; LZT-Hs6
  [Similar Products]
NCBI Protein Information
zinc transporter ZIP8
UniProt Protein Name
Zinc transporter ZIP8
UniProt Synonym Protein Names
BCG-induced integral membrane protein in monocyte clone 103 protein; LIV-1 subfamily of ZIP zinc transporter 6; LZT-Hs6; Solute carrier family 39 member 8; Zrt- and Irt-like protein 8; ZIP-8
UniProt Gene Name
SLC39A8  [Similar Products]
UniProt Synonym Gene Names
BIGM103; ZIP8; LZT-Hs6; ZIP-8  [Similar Products]
NCBI Summary for BIGM103
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]
UniProt Comments for BIGM103
Acts as a manganese and zinc influx transporter (PubMed:12504855, PubMed:26637978). Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain (PubMed:26637978).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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