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anti-CACNB1 antibody :: Rabbit anti-Human CACNB1 Polyclonal Antibody

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Catalog # MBS7043848
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

CACNB1, Polyclonal Antibody

Popular Item
Full Product Name

CACNB1 Antibody

Product Synonym Names
Voltage-dependent L-type calcium channel subunit beta-1; CAB1; Calcium channel voltage-dependent subunit beta 1; CACNB1; CACNLB1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
114207
3D Structure
ModBase 3D Structure for Q02641
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Voltage-dependent L-type calcium channel subunit beta-1 protein (C-170AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32080 / sc-32081 / sc-32079 / sc-32077 / sc-25689
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CACNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CACNB1 antibody
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Applications Tested/Suitable for anti-CACNB1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-CACNB1 antibody
Western blot
All lanes: CACNB1 antibody at 6.68 ug/ml
+ HepG-2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 66,58,54 kDa
Observed band size: 66 kDa

anti-CACNB1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CACNB1 antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7043848 at dilution 1:100
anti-CACNB1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CACNB1 antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7043848 at dilution 1:100
anti-CACNB1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CACNB1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,006 Da
NCBI Official Full Name
voltage-dependent L-type calcium channel subunit beta-1 isoform 1
NCBI Official Synonym Full Names
calcium voltage-gated channel auxiliary subunit beta 1
NCBI Official Symbol
CACNB1  [Similar Products]
NCBI Official Synonym Symbols
CAB1; CCHLB1; CACNLB1
  [Similar Products]
NCBI Protein Information
voltage-dependent L-type calcium channel subunit beta-1
UniProt Protein Name
Voltage-dependent L-type calcium channel subunit beta-1
UniProt Synonym Protein Names
Calcium channel voltage-dependent subunit beta 1
UniProt Gene Name
CACNB1  [Similar Products]
UniProt Synonym Gene Names
CACNLB1; CAB1  [Similar Products]
UniProt Entry Name
CACB1_HUMAN
NCBI Summary for CACNB1
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for CACNB1
CACNB1: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Belongs to the calcium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, calcium

Chromosomal Location of Human Ortholog: 17q21-q22

Cellular Component: plasma membrane

Molecular Function: high voltage-gated calcium channel activity; voltage-gated calcium channel activity

Biological Process: neuromuscular junction development; synaptic transmission; transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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