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anti-CNR2 antibody :: Goat Cannabinoid Receptor 2 Polyclonal Antibody

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Catalog # MBS420135
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Cannabinoid Receptor 2 (CNR2), Polyclonal Antibody

Also Known As

Goat anti-Cannabinoid Receptor 2 Antibody

Product Synonym Names
CNR2; cannabinoid receptor 2 (macrophage); HGNC: 2160; CNR3; CB2; CX5; OTTHUMP00000044841; RP11-4M23.1; testis-dominant CNR2 isoform CB2; cannabinoid receptor 2 (macrophage) antibody; HGNC: 2160 antibody; CNR3 antibody; CB2 antibody; CX5 antibody; OTTHUMP00000044841 antibody; CNR2 antibody; RP11-4M23.1 antibody; testis-dominant CNR2 isoform CB2 antibody; Cannabinoid Receptor 2; Cannabinoid Receptor 2
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
Immunogen Sequence
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
100ug specific antibody in 200ul (lot specific)
Peptide with sequence C-TETEADGKITPWPD, from the C Terminus of the protein sequence according to NP_001832.1.
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CNR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CNR2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-CNR2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 40kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 46.2kDa according to NP_001832.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 1.5-4.5ug/ml.

Western Blot (WB) of anti-CNR2 antibody
(1.5ug/ml) staining of Human Brain (Hippocampus) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-CNR2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CNR2. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,681 Da
NCBI Official Full Name
cannabinoid receptor 2
NCBI Official Synonym Full Names
cannabinoid receptor 2
NCBI Official Symbol
NCBI Official Synonym Symbols
CB2; CX5; CB-2
  [Similar Products]
NCBI Protein Information
cannabinoid receptor 2
UniProt Protein Name
Cannabinoid receptor 2
UniProt Synonym Protein Names
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
CB2A; CB2B; CB-2; CB2; hCB2  [Similar Products]
UniProt Entry Name
NCBI Summary for CNR2
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
UniProt Comments for CNR2
CNR2: Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: dendrite; extrinsic to internal side of plasma membrane; integral to plasma membrane; perikaryon; plasma membrane

Molecular Function: cannabinoid receptor activity

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; immune response; inflammatory response; negative regulation of action potential; negative regulation of inflammatory response; negative regulation of mast cell activation; negative regulation of nitric-oxide synthase activity; negative regulation of synaptic transmission, GABAergic; response to amphetamine; response to lipopolysaccharide; sensory perception of pain
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