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anti-Casp1 antibody :: Rabbit anti-Human Caspase-1 Polyclonal Antibody

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Catalog # MBS2535201
Unit / Price
Scan QR to view Datasheet
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

Caspase-1 (Casp1), Polyclonal Antibody

Popular Item
Full Product Name

Cleaved-Caspase-1 (D210) Polyclonal Antibody

Product Synonym Names
CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (lot specific)
Immunogen
Synthesized peptide derived from the Internal region of human Caspase-1.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-Casp1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-Casp1 antibody
Applications Tested/Suitable for anti-Casp1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-Casp1 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-Casp1 antibody
Western Blot analysis of NIH-3T3 cells using Cleaved-Caspase-1 (D210) Polyclonal Antibody at dilution of 1:1000.
anti-Casp1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-Casp1 antibody
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using Cleaved-Caspase-1 (D210) Polyclonal Antibody at dilution of 1:200.
anti-Casp1 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-Casp1 antibody
Immunofluorescence analysis of Human stomach cancer tissue using Cleaved-Caspase-1 (D210) Polyclonal Antibody at dilution of 1:200.
anti-Casp1 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for Casp1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Related Accession #
Molecular Weight
Calculated MW: 45
Observed MW: 25[Similar Products]
NCBI Official Full Name
caspase-1
NCBI Official Synonym Full Names
caspase 1
NCBI Official Symbol
Casp1  [Similar Products]
NCBI Official Synonym Symbols
Ice; Il1bc
  [Similar Products]
NCBI Protein Information
caspase-1
UniProt Protein Name
Caspase-1
UniProt Synonym Protein Names
Interleukin-1 beta convertase; IL-1BC
Protein Family
UniProt Gene Name
Casp1  [Similar Products]
UniProt Synonym Gene Names
Il1bc; Il1bce; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme  [Similar Products]
UniProt Entry Name
CASP1_RAT
NCBI Summary for Casp1
apoptotic protease that may play a role in inflammation and apoptosis in male sex organs [RGD, Feb 2006]
UniProt Comments for Casp1
CASP1: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis (By similarity)

Protein type: Apoptosis; EC 3.4.22.36; Protease
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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