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anti-CASP11 antibody :: Rabbit anti-Human Caspase 11 Polyclonal Antibody

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Catalog # MBS2027686 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $105 +1 FREE 8GB USB
  0.02 mg  /  $125 +1 FREE 8GB USB
  0.05 mg  /  $165 +1 FREE 8GB USB
  0.1 mg  /  $210 +1 FREE 8GB USB
  0.2 mg  /  $305 +1 FREE 8GB USB
  1 mg  /  $720 +1 FREE 8GB USB
Product Name

Caspase 11 (CASP11), Polyclonal Antibody

Popular Item
Full Product Name

Polyclonal Antibody to Caspase 11 (CASP11)

Matching Pairs
Unconjugated Antibody: Caspase 11 (MBS2027686)
Immunogen: Caspase 11 (MBS2029076)
Matching Pairs
Unconjugated Antibody: Caspase 11 (MBS2027686)
APC-CY7 Conjugated Antibody: Caspase 11 (CASP11) (MBS2037601)
Matching Pairs
Unconjugated Antibody: Caspase 11 (MBS2027686)
PE Conjugated Antibody: Caspase 11 (CASP11) (MBS2037602)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
Y11251 mRNA
3D Structure
ModBase 3D Structure for Q99590
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody is a rabbit polyclonal antibody raised against CASP11. It has beenselected for its ability to recognize CASP11 in immunohistochemical staining andwestern blotting.
Purity/Purification
Antigen-specific Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
200ug/ml (lot specific)
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant CASP11 (Arg944~Trp1148) expressed in E.coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2037603
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CASP11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CASP11 antibody
WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM
Application Notes for anti-CASP11 antibody
Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user

Western Blot (WB) of anti-CASP11 antibody
Western Blot: Sample: Recombinant CASP11, Human.
anti-CASP11 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CASP11 antibody
DAB staining on IHC-P; Samples: Human Prostate Gland Tissue
anti-CASP11 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CASP11 antibody
DAB staining on IHC-P; Samples: Human Pancreas Cancer Tissue.
anti-CASP11 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CASP11 antibody
DAB staining on IHC-P; Samples: Human Prostate Gland Cancer Tissue.
anti-CASP11 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CASP11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
128,875 Da
NCBI Official Full Name
protein SCAF11
NCBI Official Synonym Full Names
SR-related CTD associated factor 11
NCBI Official Symbol
SCAF11  [Similar Products]
NCBI Official Synonym Symbols
SIP1; CASP11; SFRS2IP; SRRP129; SRSF2IP
  [Similar Products]
NCBI Protein Information
protein SCAF11
UniProt Protein Name
Protein SCAF11
UniProt Synonym Protein Names
CTD-associated SR protein 11; Renal carcinoma antigen NY-REN-40; SC35-interacting protein 1; SR-related and CTD-associated factor 11; SRSF2-interacting protein; Serine/arginine-rich splicing factor 2-interacting protein; Splicing factor, arginine/serine-rich 2-interacting protein; Splicing regulatory protein 129; SRrp129
UniProt Gene Name
SCAF11  [Similar Products]
UniProt Synonym Gene Names
CASP11; SFRS2IP; SIP1; SRSF2IP; SRrp129  [Similar Products]
UniProt Comments for CASP11
SFRS2IP: Plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA processing; RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: nuclear body; nucleolus; nucleoplasm; nucleus

Molecular Function: metal ion binding; protein binding; RNA binding

Biological Process: mRNA processing; RNA splicing; RNA splicing, via transesterification reactions; spliceosomal complex assembly
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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