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anti-Casp2 antibody :: Rabbit anti-Human Caspase-2 Polyclonal Antibody

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Catalog # MBS2539198
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Caspase-2 (Casp2), Polyclonal Antibody

Popular Item
Also Known As

Caspase-2 Polyclonal Antibody

Product Synonym Names
CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
452
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (lot specific)
Immunogen
Synthesized peptide derived from human Caspase-2 around the non-phosphorylation site of S157.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-Casp2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-Casp2 antibody
Applications Tested/Suitable for anti-Casp2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-Casp2 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-Casp2 antibody
Western Blot analysis of various cells with Caspase-2 Polyclonal Antibody.
anti-Casp2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for Casp2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW: 51
Observed MW: 51[Similar Products]
NCBI Official Full Name
caspase-2
NCBI Official Synonym Full Names
caspase 2
NCBI Official Symbol
Casp2  [Similar Products]
NCBI Protein Information
caspase-2
UniProt Protein Name
Caspase-2
UniProt Synonym Protein Names
Protease ICH-1
Protein Family
UniProt Gene Name
Casp2  [Similar Products]
UniProt Synonym Gene Names
Ich1; CASP-2  [Similar Products]
UniProt Entry Name
CASP2_RAT
NCBI Summary for Casp2
may play a role in proteolysis and programmed cell death [RGD, Feb 2006]
UniProt Comments for Casp2
CASP2: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD. Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle. Belongs to the peptidase C14A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; EC 3.4.22.55; Apoptosis

Cellular Component: cytoplasm; membrane; mitochondrion; nucleus

Molecular Function: cysteine-type endopeptidase activity; protein binding; protein domain specific binding

Biological Process: aging; apoptosis; brain development; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; germ cell programmed cell death; luteolysis; positive regulation of apoptosis; positive regulation of neuron apoptosis; programmed cell death; protein processing; proteolysis; regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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