NP_005614.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
C-C motif chemokine 8
NCBI Official Synonym Full Names
C-C motif chemokine ligand 8
NCBI Official Synonym Symbols
HC14; MCP2; MCP-2; SCYA8; SCYA10 [Similar Products]
NCBI Protein Information
C-C motif chemokine 8
UniProt Protein Name
C-C motif chemokine 8
UniProt Synonym Protein Names
HC14; Monocyte chemoattractant protein 2; Monocyte chemotactic protein 2; MCP-2
UniProt Synonym Gene Names
NCBI Summary for CCL8
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]
UniProt Comments for CCL8
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Research Articles on CCL8
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Products associated with anti-CCL8 antibody
Pathways associated with anti-CCL8 antibody
Diseases associated with anti-CCL8 antibody
Organs/Tissues associated with anti-CCL8 antibody
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