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anti-CD109 antibody :: Rabbit anti-Human CD109 Polyclonal Antibody

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Catalog # MBS2530288
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

CD109, Polyclonal Antibody

Popular Item
Also Known As

CD109 Polyclonal Antibody

Product Synonym Names
CPAMD7; RP11-525G3.1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2530288 Technical Datasheet
Immunogen Sequence Length
1368
OMIM
608859
3D Structure
ModBase 3D Structure for Q6YHK3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity purification
Immunogen
Synthetic peptide of human CD109
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CD109 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD109 antibody
This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
Applications Tested/Suitable for anti-CD109 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-CD109 antibody
IHC: 1:25-1:100

Immunohistochemistry (IHC) of anti-CD109 antibody
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD109 Polyclonal Antibody at dilution 1:30
anti-CD109 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CD109 antibody
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CD109 Polyclonal Antibody at dilution 1:30
anti-CD109 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CD109. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CD109 antigen isoform 3 preproprotein
NCBI Official Synonym Full Names
CD109 molecule
NCBI Official Symbol
CD109  [Similar Products]
NCBI Official Synonym Symbols
p180; r150; CPAMD7
  [Similar Products]
NCBI Protein Information
CD109 antigen; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Gov platelet alloantigens; activated T-cell marker CD109; platelet-specific Gov antigen
UniProt Protein Name
CD109 antigen
UniProt Synonym Protein Names
150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Platelet-specific Gov antigen; p180; r150; CD_antigen: CD109
Protein Family
UniProt Gene Name
CD109  [Similar Products]
UniProt Synonym Gene Names
CPAMD7  [Similar Products]
UniProt Entry Name
CD109_HUMAN
NCBI Summary for CD109
This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
UniProt Comments for CD109
CD109: Modulates negatively TGFB1 signaling in keratinocytes. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 6q13

Cellular Component: extracellular space; cell surface; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity; transforming growth factor beta binding

Biological Process: negative regulation of protein amino acid phosphorylation; hair follicle development; negative regulation of transforming growth factor beta receptor signaling pathway; regulation of keratinocyte differentiation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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