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anti-CDH6 antibody :: Rabbit anti-Human CDH6 Polyclonal Antibody

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Catalog # MBS1495594
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

CDH6, Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human CDH6 polyclonal Antibody

Product Synonym Names
Kidney cadherin; K-cadherin; CDH6
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
790
OMIM
603007
3D Structure
ModBase 3D Structure for P55285
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cadherin-6 protein (1-250aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31024 / sc-1503
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CDH6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CDH6 antibody
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Applications Tested/Suitable for anti-CDH6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CDH6 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-CDH6 antibody
All lanes: CDH6 antibody at 6ug/ml
Lane 1:293T whole cell lysate
Lane 2:Hela whole cell lysate
Lane 3:A549 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 89,74 kDa
Observed band size: 88 kDa

anti-CDH6 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CDH6 antibody
Immunohistochemistry of paraffin-embedded human kidney using MBS1495594 at dilution 1:100
anti-CDH6 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CDH6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
73,864 Da
NCBI Official Full Name
cadherin-6 preproprotein
NCBI Official Synonym Full Names
cadherin 6
NCBI Official Symbol
NCBI Official Synonym Symbols
CAD6; KCAD
  [Similar Products]
NCBI Protein Information
cadherin-6
UniProt Protein Name
Cadherin-6
UniProt Synonym Protein Names
Kidney cadherin; K-cadherin
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
K-cadherin  [Similar Products]
UniProt Entry Name
CADH6_HUMAN
NCBI Summary for CDH6
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
UniProt Comments for CDH6
CDH6: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 5p13.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: calcium ion binding

Biological Process: cell adhesion; homophilic cell adhesion; intercellular junction assembly and maintenance; Notch signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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