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anti-CEACAM1 antibody :: Rabbit anti-Human CEACAM1 Polyclonal Antibody

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Catalog # MBS7000563
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CEACAM1, Polyclonal Antibody

Popular Item
Also Known As

CEACAM1 Antibody

Product Synonym Names
Carcinoembryonic antigen-related cell adhesion molecule 1; CEACAM1; BGP; BGP1; Biliary glycoprotein 1; BGP-1; CD_antigen: CD66a
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
464
OMIM
109770
3D Structure
ModBase 3D Structure for P13688
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purified
Form/Format
Liquid
Immunogen
Recombinant human Carcinoembryonic antigen-related cell adhesion molecule 1 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54289 / sc-54287 / sc-17068 / sc-8222 / sc-8223 / sc-25627
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CEACAM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CEACAM1 antibody
extracellular exosome, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane, protein homodimerization activity, angiogenesis, blood coagulation, cell migration, homophilic cell adhesion via plasma membrane adhesion molecules
Applications Tested/Suitable for anti-CEACAM1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CEACAM1 antibody
Recommended dilution: WB:1:500-2000

Western Blot (WB) of anti-CEACAM1 antibody
Western blot
All lanes: CEACAM1 antibody at 10ug/ml
Lane 1: HT29 whole cell lysate
Lane 2: HCT116 whole cell lysate
Lane 3: COLO205 whole cell lysate
Lane 4: HepG-2 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 58,46,36,39,51,47,28,44,52 kDa
Observed band size: 58 kDa

anti-CEACAM1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CEACAM1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,871 Da
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 1 isoform 2
NCBI Official Synonym Full Names
carcinoembryonic antigen related cell adhesion molecule 1
NCBI Official Symbol
CEACAM1  [Similar Products]
NCBI Official Synonym Symbols
BGP; BGP1; BGPI
  [Similar Products]
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 1
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 1
UniProt Synonym Protein Names
Biliary glycoprotein 1; BGP-1; CD_antigen: CD66a
Protein Family
UniProt Gene Name
CEACAM1  [Similar Products]
UniProt Synonym Gene Names
BGP; BGP1; BGP-1  [Similar Products]
UniProt Entry Name
CEAM1_HUMAN
NCBI Summary for CEACAM1
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
UniProt Comments for CEACAM1
CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: integral to membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: protein binding; protein homodimerization activity

Biological Process: angiogenesis; blood coagulation; cell migration; homophilic cell adhesion; integrin-mediated signaling pathway; leukocyte migration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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