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anti-CNTN4 antibody :: Rabbit anti-Human CNTN4 Polyclonal Antibody

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Catalog # MBS7045279
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

CNTN4, Polyclonal Antibody

Popular Item
Full Product Name

CNTN4 Antibody

Product Synonym Names
Contactin-4; Brain-derived immunoglobulin superfamily protein 2; BIG-2; CNTN4
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
607280
3D Structure
ModBase 3D Structure for Q8IWV2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Contactin-4 protein (C-250AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68161 / sc-68162 / sc-68856
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-CNTN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CNTN4 antibody
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.
Applications Tested/Suitable for anti-CNTN4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-CNTN4 antibody
Western blot
All lanes: CNTN4 antibody IgG at 1.79ug/ml+ HepG-2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 114,32,77 kDa
Observed band size: 113 kDa

anti-CNTN4 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CNTN4 antibody
Immunohistochemistry of paraffin-embedded human brain tissue MBS7045279 at dilution 1:100
anti-CNTN4 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CNTN4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,655 Da
NCBI Official Full Name
contactin-4 isoform a
NCBI Official Synonym Full Names
contactin 4
NCBI Official Symbol
CNTN4  [Similar Products]
NCBI Official Synonym Symbols
AXCAM; BIG-2
  [Similar Products]
NCBI Protein Information
contactin-4
UniProt Protein Name
Contactin-4
UniProt Synonym Protein Names
Brain-derived immunoglobulin superfamily protein 2; BIG-2
Protein Family
UniProt Gene Name
CNTN4  [Similar Products]
UniProt Synonym Gene Names
BIG-2  [Similar Products]
UniProt Entry Name
CNTN4_HUMAN
NCBI Summary for CNTN4
This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
UniProt Comments for CNTN4
CNTN4: Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis. A chromosomal aberration involving CNTN4 has been found in a boy with characteristic physical features of 3p deletion syndrome (3PDS). Translocation t(3;10)(p26;q26). 3PDS is a rare contiguous gene disorder involving the loss of the telomeric portion of the short arm of chromosome 3 and characterized by developmental delay, growth retardation, and dysmorphic features. Belongs to the immunoglobulin superfamily. Contactin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 3p26.3

Biological Process: axon guidance; axonal fasciculation; axonogenesis; brain development; negative regulation of neuron differentiation; nervous system development; neurite development; neuron adhesion; regulation of synaptic plasticity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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