• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-COL8A1 antibody :: Rabbit anti-Human COL8A1 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS7004232
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

COL8A1, Polyclonal Antibody

Popular Item
Full Product Name

COL8A1 Antibody

Product Synonym Names
Collagen alpha-1(VIII) chain; Endothelial collagen; COL8A1; C3orf7
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
120251
3D Structure
ModBase 3D Structure for P27658
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Immunogen
Recombinant human Collagen alpha-1(VIII) chain protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-99356 / sc-99357
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-COL8A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-COL8A1 antibody
Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
Applications Tested/Suitable for anti-COL8A1 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Western Blot (WB) of anti-COL8A1 antibody
Western Blot
Positive WB detected in:HepG2 whole cell lysate,Hela whole cell lysate,Mouse heart tissue,Mouse liver tissue,Mouse lung tissue,Mouse kidney tissue,Mouse brain tissue,Mouse skeletal muscle tissue
All lanes: COL8A1 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 74 kDa
Observed band size: 74,50 kDa

anti-COL8A1 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-COL8A1 antibody
Immunofluorescent analysis of U251 cells using MBS7004232 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-COL8A1 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for COL8A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
73,364 Da
NCBI Official Full Name
collagen alpha-1(VIII) chain
NCBI Official Synonym Full Names
collagen type VIII alpha 1
NCBI Official Symbol
COL8A1  [Similar Products]
NCBI Official Synonym Symbols
C3orf7
  [Similar Products]
NCBI Protein Information
collagen alpha-1(VIII) chain
UniProt Protein Name
Collagen alpha-1(VIII) chain
UniProt Synonym Protein Names
Endothelial collagen
Protein Family
UniProt Gene Name
COL8A1  [Similar Products]
UniProt Synonym Gene Names
C3orf7  [Similar Products]
UniProt Entry Name
CO8A1_HUMAN
NCBI Summary for COL8A1
This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Dec 2011]
UniProt Comments for COL8A1
COL8A1: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.

Protein type: Secreted, signal peptide; Secreted; Extracellular matrix

Chromosomal Location of Human Ortholog: 3q12.3

Cellular Component: collagen type VIII; endoplasmic reticulum lumen; extracellular matrix; extracellular region; intracellular membrane-bound organelle

Molecular Function: protein binding

Biological Process: angiogenesis; camera-type eye morphogenesis; cell adhesion; collagen catabolic process; epithelial cell proliferation; extracellular matrix disassembly; extracellular matrix organization and biogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000