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anti-CRTAP antibody :: Rabbit anti-Human CRTAP Polyclonal Antibody

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Catalog # MBS7045246
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

CRTAP, Polyclonal Antibody

Popular Item
Also Known As

CRTAP Antibody

Product Synonym Names
Cartilage-associated protein; CRTAP; CASP
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
401
OMIM
605497
3D Structure
ModBase 3D Structure for O75718
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Cartilage-associated protein (20-240AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-99366 / sc-99367
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CRTAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CRTAP antibody
Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
Applications Tested/Suitable for anti-CRTAP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-CRTAP antibody
Western blot
All lanes: CRTAP antibody at 0.96ug/ml
Lane 1: 293T whole cell lysate
Lane 2: Hela whole cell lysate
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 47 kDa
Observed band size: 47 kDa

anti-CRTAP antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CRTAP antibody
Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045246 at dilution 1:100
anti-CRTAP antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CRTAP antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045246 at dilution 1:100
anti-CRTAP antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CRTAP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,562 Da
NCBI Official Full Name
cartilage-associated protein
NCBI Official Synonym Full Names
cartilage associated protein
NCBI Official Symbol
CRTAP  [Similar Products]
NCBI Official Synonym Symbols
OI7; CASP; P3H5; LEPREL3
  [Similar Products]
NCBI Protein Information
cartilage-associated protein
UniProt Protein Name
Cartilage-associated protein
UniProt Gene Name
CRTAP  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
CRTAP_HUMAN
NCBI Summary for CRTAP
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. [provided by RefSeq, Jul 2008]
UniProt Comments for CRTAP
CRTAP: Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues. Defects in CRTAP are the cause of osteogenesis imperfecta type 7 (OI7). A connective tissue disorder characterized by short stature, short humeri and femora, coxa vara, white sclera, and the absence of dentinogenesis imperfecta. Multiple fractures are present at birth, and patients manifest moderate-severe bone fragility. Death may occurr in the perinatal period due to secondary respiratory insufficiency. Belongs to the leprecan family.

Protein type: Secreted; Secreted, signal peptide; Extracellular matrix

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; extracellular space

Molecular Function: protein complex binding

Biological Process: protein stabilization

Disease: Osteogenesis Imperfecta, Type Vii
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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