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anti-CRYBA1 antibody :: Rabbit anti-Human CRYBA1 Polyclonal Antibody

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Catalog # MBS7006779
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CRYBA1, Polyclonal Antibody

Popular Item
Also Known As

CRYBA1 Antibody

Product Synonym Names
Beta-crystallin A3Cleaved into the following 3 chains:Beta-crystallin A3; isoform A1; Delta4 formBeta-crystallin A3; isoform A1; Delta7 formBeta-crystallin A3; isoform A1; Delta8 form; CRYBA1; CRYB1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
215
OMIM
123610
3D Structure
ModBase 3D Structure for P05813
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Immunogen
Recombinant human Beta-crystallin A3 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22398
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CRYBA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CRYBA1 antibody
Crystallins are the dominant structural components of the vertebrate eye lens.
Applications Tested/Suitable for anti-CRYBA1 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-CRYBA1 antibody
Western blot
All lanes: CRYBA1 antibody at 6ug/ml
Lane 1: Mouse heart tissue
Lane 2: Human placenta tissue
Lane 3: U251 whole cell lysate
Lane 4: U937 whole cell lysate
Lane 5: Mouse stomach tissue
Lane 6: Mouse liver tissue
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 26,24 kDa
Observed band size: 25 kDa

anti-CRYBA1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CRYBA1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,191 Da
NCBI Official Full Name
beta-crystallin A3
NCBI Official Synonym Full Names
crystallin beta A1
NCBI Official Symbol
CRYBA1  [Similar Products]
NCBI Official Synonym Symbols
CRYB1; CTRCT10
  [Similar Products]
NCBI Protein Information
beta-crystallin A3
UniProt Protein Name
Beta-crystallin A3
Protein Family
UniProt Gene Name
CRYBA1  [Similar Products]
UniProt Synonym Gene Names
CRYB1  [Similar Products]
UniProt Entry Name
CRBA1_HUMAN
NCBI Summary for CRYBA1
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. [provided by RefSeq, Jul 2008]
UniProt Comments for CRYBA1
CRYBA1: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital zonular cataract with sutural opacities. Two splice-variant isoforms have been described.

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; protein homodimerization activity; structural constituent of eye lens

Biological Process: lens development in camera-type eye; negative regulation of cytokine production; negative regulation of phosphoinositide 3-kinase cascade; negative regulation of protein kinase B signaling cascade; negative regulation of TOR signaling pathway; visual perception

Disease: Cataract 10, Multiple Types
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-CRYBA1 antibody
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