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anti-CXCL1 antibody :: Rabbit anti-Human CXCL1 Polyclonal Antibody

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Catalog # MBS8241868
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CXCL1, Polyclonal Antibody

Popular Item
Also Known As

Anti-CXCL1 Antibody

Product Synonym Names
GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3
Antibody/Peptide Pairs
CXCL1 peptide (MBS8244222) is used for blocking the activity of CXCL1 antibody (MBS8241868)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
107
OMIM
155730
3D Structure
ModBase 3D Structure for P09341
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Specificity
Recognizes endogenous levels of CXCL1 protein.
Purity/Purification
The antibody was purified by affinity chromatography.
Form/Format
Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% Sodium Azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CXCL1. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-CXCL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CXCL1 antibody
Rabbit polyclonal antibody to CXCL1
Applications Tested/Suitable for anti-CXCL1 antibody
Western Blot (WB)
Application Notes for anti-CXCL1 antibody
Western Blot: (1/500 - 1/1000)

Western Blot (WB) of anti-CXCL1 antibody
Western blot analysis of CXCL1 expression in Jurkat (A), Hela (B) whole cell lysates.
anti-CXCL1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CXCL1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,301 Da
NCBI Official Full Name
Growth-regulated alpha protein
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 1
NCBI Official Symbol
CXCL1  [Similar Products]
NCBI Official Synonym Symbols
FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
  [Similar Products]
NCBI Protein Information
growth-regulated alpha protein
UniProt Protein Name
Growth-regulated alpha protein
UniProt Synonym Protein Names
C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA
UniProt Gene Name
CXCL1  [Similar Products]
UniProt Synonym Gene Names
GRO; GRO1; GROA; MGSA; SCYB1; MGSA; NAP-3  [Similar Products]
UniProt Entry Name
GROA_HUMAN
NCBI Summary for CXCL1
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
UniProt Comments for CXCL1
CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular region; extracellular space; intracellular

Molecular Function: chemokine activity; CXCR chemokine receptor binding; enzyme activator activity; growth factor activity; receptor binding

Biological Process: actin cytoskeleton organization and biogenesis; cell proliferation; chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; negative regulation of cell proliferation; nervous system development; positive regulation of catalytic activity; response to lipopolysaccharide; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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