NP_940879.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,819 Da
NCBI Official Full Name
C-X-C motif chemokine 17
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 17
NCBI Official Synonym Symbols
DMC; VCC1; Dcip1; VCC-1; UNQ473 [Similar Products]
NCBI Protein Information
C-X-C motif chemokine 17
UniProt Protein Name
C-X-C motif chemokine 17
UniProt Synonym Protein Names
Dendritic cell and monocyte chemokine-like protein; DMC
UniProt Synonym Gene Names
UniProt Entry Name
CXL17_HUMAN
NCBI Summary for CXCL17
The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]
UniProt Comments for CXCL17
CXCL17: Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: extracellular space
Biological Process: activation of MAPK activity; negative regulation of inflammatory response
Research Articles on CXCL17
Precautions
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Disclaimer
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Products associated with anti-CXCL17 antibody
Diseases associated with anti-CXCL17 antibody
Organs/Tissues associated with anti-CXCL17 antibody
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