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anti-CXCL2 antibody :: Goat CXCL2/MIP-2 Polyclonal Antibody

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Catalog # MBS422140
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Product Name

CXCL2/MIP-2, Polyclonal Antibody

Also Known As

Goat anti-CXCL2/MIP-2 Antibody

Product Synonym Names
CXCL2; chemokine (C-X-C motif) ligand 2; CINC-2a; GRO2; GROb; MGSA-b; MIP-2a; MIP2; MIP-2; MIP2A; SCYB2; GRO2 oncogene; MGSA beta; melanoma growth stimulatory activity beta; Macrophage Inflammatory Protein-2; CXCL2 antibody; chemokine (C-X-C motif) ligand 2 antibody; CINC-2a antibody; GRO2 antibody; GROb antibody; MGSA-b antibody; MIP-2a antibody; MIP2 antibody; MIP2A antibody; SCYB2 antibody; GRO2 oncogene antibody; MGSA beta antibody; melanoma growth stimulatory activity beta antibody; CXCL2 / MIP-2
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
107
Immunogen Sequence
KKIIEKMLKN GKSN
OMIM
139110
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-KKIIEKMLKNGKSN, from the C Terminus of the protein sequence according to NP_002080.1.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CXCL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CXCL2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-CXCL2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.

Western Blot (WB) of anti-CXCL2 antibody
(0. 03ug/ml) staining of Daudi lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
anti-CXCL2 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-CXCL2 antibody
(0.2ug/ml) staining of Human Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
anti-CXCL2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CXCL2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,389 Da
NCBI Official Full Name
C-X-C motif chemokine 2
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 2
NCBI Official Symbol
CXCL2  [Similar Products]
NCBI Official Synonym Symbols
GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
  [Similar Products]
NCBI Protein Information
C-X-C motif chemokine 2
UniProt Protein Name
C-X-C motif chemokine 2
UniProt Synonym Protein Names
Growth-regulated protein beta; Gro-beta
Protein Family
UniProt Gene Name
CXCL2  [Similar Products]
UniProt Synonym Gene Names
GRO2; GROB; MIP2A; SCYB2; Gro-beta; MIP2-alpha; HSF  [Similar Products]
UniProt Entry Name
CXCL2_HUMAN
NCBI Summary for CXCL2
This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]
UniProt Comments for CXCL2
CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular region

Molecular Function: CXCR chemokine receptor binding; protein binding

Biological Process: chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; regulation of cell proliferation; response to lipopolysaccharide; response to molecule of bacterial origin
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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