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anti-CXCR6 antibody :: Rabbit anti-Human CXCR6 Polyclonal Antibody

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Catalog # MBS242091
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

CXCR6, Polyclonal Antibody

Popular Item
Also Known As

Rabbit Polyclonal to Human CXCR6

Product Synonym Names
Anti-CXCR6 Antibody (N-Terminus) IHC-plus; CXCR6; CD186 antigen; CXCR-6; STRL33; TYMSTR; BONZO; CD186; CDw186; CXC-R6; Human CXCR6
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
342
OMIM
605163
3D Structure
ModBase 3D Structure for O00574
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Specificity
peptide corresponding to amino acids near the amino terminus of human Bonzo/STRL33 The sequence of this peptide differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively,
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide from human CXCR6.
Immunogen Type
Synthetic peptide
Immunogen
CXCR6 antibody was raised against synthetic peptide from human CXCR6.
Antigen Modification
N-Terminus
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Other Notes
Small volumes of anti-CXCR6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CXCR6 antibody
Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells.
Applications Tested/Suitable for anti-CXCR6 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-CXCR6 antibody
IHC-P (2.5 ug/ml), WB (1:500)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-CXCR6 antibody
Anti-CXCR6 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-CXCR6 antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-CXCR6 antibody
Western blot of Bonzo in human spleen tissue lysate in the absence (lane A) or presence (lane B) of peptide with Bonzo antibody at 1 ug/ml.
anti-CXCR6 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CXCR6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,280 Da
NCBI Official Full Name
C-X-C chemokine receptor type 6
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 6
NCBI Official Symbol
CXCR6  [Similar Products]
NCBI Official Synonym Symbols
BONZO; CD186; STRL33; TYMSTR
  [Similar Products]
NCBI Protein Information
C-X-C chemokine receptor type 6; CDw186; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33
UniProt Protein Name
C-X-C chemokine receptor type 6
UniProt Synonym Protein Names
CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD_antigen: CD186
Protein Family
UniProt Gene Name
CXCR6  [Similar Products]
UniProt Synonym Gene Names
BONZO; STRL33; TYMSTR; CXC-R6; CXCR-6  [Similar Products]
UniProt Entry Name
CXCR6_HUMAN
UniProt Comments for CXCR6
CXCR6: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; coreceptor activity; C-X-C chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; viral genome replication; inflammatory response; chemotaxis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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