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anti-CYP2F1 antibody :: Rabbit anti-Human Cytochrome P450 2F1 Polyclonal Antibody

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Catalog # MBS1496173
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

Cytochrome P450 2F1 (CYP2F1), Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human Cytochrome P450 2F1 polyclonal Antibody(CYP2F1)

Product Synonym Names
CYPIIF1; CYP2F1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
491
OMIM
124070
3D Structure
ModBase 3D Structure for P24903
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cytochrome P450 2F1 protein (100-290aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66360 / sc-67283 / sc-67282
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CYP2F1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CYP2F1 antibody
May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3-methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine.
Applications Tested/Suitable for anti-CYP2F1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CYP2F1 antibody
Recommended dilution: WB:1:200-1000
IHC:1:20-1:200

Western Blot (WB) of anti-CYP2F1 antibody
All lanes: Cytochrome P450 2F1 antibody at 8ug/ml+A549 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 56,37 kDa
Observed band size: 56 kDa

anti-CYP2F1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CYP2F1 antibody
Immunohistochemistry of paraffin-embedded human lung using MBS1496173 at dilution 1:100
anti-CYP2F1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CYP2F1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,410 Da
NCBI Official Full Name
cytochrome P450 2F1
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily F member 1
NCBI Official Symbol
CYP2F1  [Similar Products]
NCBI Official Synonym Symbols
C2F1; CYP2F
  [Similar Products]
NCBI Protein Information
cytochrome P450 2F1
UniProt Protein Name
Cytochrome P450 2F1
UniProt Synonym Protein Names
CYPIIF1
Protein Family
UniProt Gene Name
CYP2F1  [Similar Products]
UniProt Entry Name
CP2F1_HUMAN
NCBI Summary for CYP2F1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
UniProt Comments for CYP2F1
CYP2F2: May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3- methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine. Belongs to the cytochrome P450 family.

Protein type: Oxidoreductase; EC 1.14.14.1; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle

Molecular Function: arachidonic acid epoxygenase activity; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; oxygen binding; steroid hydroxylase activity

Biological Process: epoxygenase P450 pathway; naphthalene metabolic process; response to toxin; trichloroethylene metabolic process; xenobiotic metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-CYP2F1 antibody
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