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anti-CYP4F8 antibody :: Rabbit anti-Human Cytochrome P450 4F8 Polyclonal Antibody

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Catalog # MBS9609245
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Cytochrome P450 4F8 (CYP4F8), Polyclonal Antibody

Popular Item
Also Known As

Cytochrome P450 4F8 Antibody

Product Synonym Names
CPF8; CYP4F8; Cytochrome P450 4F8; Cytochrome P450, subfamily IVF, polypeptide 8; Microsomal monooxygenase; Polypeptide 8; flavoprotein-linked monooxygenase
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
520
3D Structure
ModBase 3D Structure for P98187
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Cytochrome P450 4F8 antibody detects endogenous levels of total Cytochrome P450 4F8
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human Cytochrome P450 4F8
Subcellular Location
Endoplasmic Reticulum Membrane; Single-Pass Membrane Protein. Microsome Membrane.
Tissue Specificity
Expressed in the epithelium of seminal vesicles, in renal cortex, in adult and fetal liver, in epidermis, in corneal epithelium, in sweat glands, hair follicles, epithelial linings of the ampulla of vas deferens and of the stomach and small intestine, as well as in the transitional epithelium of the bladder and ureter (at protein level). In the epidermis, expressed from the basal cell to the granular cell layers. In the corneal epithelium, expressed in all cell layers. Also detected in prostate. Up-regulated in the epidermis of psoriatic lesions.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CYP4F8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CYP4F8 antibody
Function: Hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. Shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4, 7, 10, 13, 16, 19-(Z)-docosahexaenoic acid (22:6n-3) and 7, 10, 13, 16, 19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4, 7, 10, 13, 16-(Z)-docosapentaenoic acid (22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.
Similarity: Belongs to the cytochrome P450 family.
Applications Tested/Suitable for anti-CYP4F8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CYP4F8 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-CYP4F8 antibody
Western blot analysis of Cytochrome P450 4F8 using Jurkat whole cell lysates
anti-CYP4F8 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CYP4F8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 60 kDa
Predicted: 60 kDa
NCBI Official Full Name
cytochrome P450 4F8
NCBI Official Synonym Full Names
cytochrome P450 family 4 subfamily F member 8
NCBI Official Symbol
CYP4F8  [Similar Products]
NCBI Official Synonym Symbols
CPF8; CYPIVF8
  [Similar Products]
NCBI Protein Information
cytochrome P450 4F8
UniProt Protein Name
Cytochrome P450 4F8
UniProt Synonym Protein Names
CYPIVF8
Protein Family
UniProt Gene Name
CYP4F8  [Similar Products]
NCBI Summary for CYP4F8
This gene, CYP4F8, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and functions as a 19-hydroxylase of prostaglandins in seminal vesicles. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F3, is approximately 18 kb away. [provided by RefSeq, Jul 2008]
UniProt Comments for CYP4F8
Hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. Shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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