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anti-GBA3 antibody :: Rabbit anti-Human Cytosolic beta-glucosidase Polyclonal Antibody

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Catalog # MBS1494091
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

Cytosolic beta-glucosidase (GBA3), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Cytosolic beta-glucosidase polyclonal Antibody(GBA3)

Product Synonym Names
Cytosolic beta-glucosidase-like protein 1; GBA3; CBG; CBGL1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
606619
3D Structure
ModBase 3D Structure for Q9H227
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cytosolic beta-glucosidase protein (1-162aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-51262 / sc-51263 / sc-51264
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-GBA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GBA3 antibody
Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
Applications Tested/Suitable for anti-GBA3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GBA3 antibody
Recommended dilution: WB:1:500-5000
IHC:1:20-1:200

Western Blot (WB) of anti-GBA3 antibody
All lanes: Cytosolic beta-glucosidase antibody at 10ug/ml
Lane 1:Hela whole cell lysate
Lane 2:HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 54,19 kDa
Observed band size: 54 kDa

anti-GBA3 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-GBA3 antibody
Immunohistochemistry of paraffin-embedded human tonsil using MBS1494091 at dilution 1:100
anti-GBA3 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-GBA3 antibody
Immunohistochemistry of paraffin-embedded human kidney using MBS1494091 at dilution 1:100
anti-GBA3 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-GBA3 antibody
Immunohistochemistry of paraffin-embedded human pancreas using MBS1494091 at dilution 1:100
anti-GBA3 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for GBA3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,265 Da
NCBI Official Full Name
cytosolic beta-glucosidase isoform b
NCBI Official Synonym Full Names
glucosidase, beta, acid 3 (gene/pseudogene)
NCBI Official Symbol
NCBI Official Synonym Symbols
CBG; GLUC; KLRP; CBGL1
  [Similar Products]
NCBI Protein Information
cytosolic beta-glucosidase
UniProt Protein Name
Cytosolic beta-glucosidase
UniProt Synonym Protein Names
Cytosolic beta-glucosidase-like protein 1
UniProt Gene Name
UniProt Synonym Gene Names
CBG; CBGL1  [Similar Products]
UniProt Entry Name
GBA3_HUMAN
NCBI Summary for GBA3
The protein encoded by this gene is an enzyme that can hydrolyze several types of glycosides. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals, as represented by the reference genome allele, contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2013]
UniProt Comments for GBA3
GBA3: Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Carbohydrate Metabolism - starch and sucrose; Other Amino Acids Metabolism - cyanoamino acid; EC 3.2.1.21

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: cytosol

Molecular Function: beta-galactosidase activity; beta-glucosidase activity; glycosylceramidase activity

Biological Process: carbohydrate metabolic process; glycoside catabolic process; glycosphingolipid metabolic process; glycosylceramide catabolic process; sphingolipid metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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