NP_055141.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,931 Da
NCBI Official Full Name
death-associated protein kinase 2
NCBI Official Synonym Full Names
death-associated protein kinase 2
NCBI Official Synonym Symbols
NCBI Protein Information
death-associated protein kinase 2
UniProt Protein Name
Death-associated protein kinase 2
UniProt Synonym Protein Names
DAP-kinase-related protein 1; DRP-1
UniProt Synonym Gene Names
UniProt Entry Name
DAPK2_HUMAN
NCBI Summary for DAPK2
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
UniProt Comments for DAPK2
DAPK2: an ubiquitously expressed protein kinase of the DAPK family. Activated by Ca(2+)/calmodulin. Contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain. Overexpression induces apoptosis. Expressed at high levels in heart, lung and skeletal muscle.
Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.1; CAMK group; DAPK family
Chromosomal Location of Human Ortholog: 15q22.31
Cellular Component: cytoplasm; cytoplasmic vesicle
Molecular Function: ATP binding; calmodulin binding; identical protein binding; protein binding; protein serine/threonine kinase activity
Biological Process: anoikis; apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of apoptosis; regulation of autophagy
Research Articles on DAPK2
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Products associated with anti-DAPK2 antibody
Pathways associated with anti-DAPK2 antibody
Diseases associated with anti-DAPK2 antibody
Organs/Tissues associated with anti-DAPK2 antibody
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