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anti-DEFA6 antibody :: Rabbit anti-Human DEFA6 Polyclonal Antibody

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Catalog # MBS2524315
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

DEFA6, Polyclonal Antibody

Popular Item
Full Product Name

DEFA6 Polyclonal Antibody

Product Synonym Names
DEF6; HD-6
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600471
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity purification
Concentration
0.5mg/mL (lot specific)
Immunogen
Recombinant protein of human DEFA6
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-DEFA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DEFA6 antibody
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8.
Applications Tested/Suitable for anti-DEFA6 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-DEFA6 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-DEFA6 antibody
Immunohistochemistry of paraffin-embedded Human brain tissue using DEFA6 Polyclonal Antibody at dilution 1:40
anti-DEFA6 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for DEFA6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
defensin-6 preproprotein
NCBI Official Synonym Full Names
defensin, alpha 6, Paneth cell-specific
NCBI Official Symbol
DEFA6  [Similar Products]
NCBI Official Synonym Symbols
DEF6; HD-6
  [Similar Products]
NCBI Protein Information
defensin-6; defensin 6
UniProt Protein Name
Defensin-6
UniProt Synonym Protein Names
Defensin, alpha 6
Protein Family
UniProt Gene Name
DEFA6  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
DEF6_HUMAN
NCBI Summary for DEFA6
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Oct 2014]
UniProt Comments for DEFA6
defensin, alpha 6: Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1. Belongs to the alpha-defensin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: extracellular space; Golgi lumen; extracellular region

Biological Process: killing of cells of another organism; antibacterial humoral response; innate immune response; defense response to fungus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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