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anti-RPN1 antibody :: Rabbit anti-Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Polyclonal Antibody

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Catalog # MBS7000935
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (RPN1), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit polyclonal Antibody

Product Synonym Names
OK/SW-cl.45; KIAA0115; OST48; DDOST; Oligosaccharyl transferase 48 kDa subunit; DDOST 48 kDa subunit
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
180470
3D Structure
ModBase 3D Structure for P04843
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Immunogen
Recombinant human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12164 / sc-12163 / sc-25559
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-RPN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RPN1 antibody
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome.
Applications Tested/Suitable for anti-RPN1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RPN1 antibody
Recommended dilution: WB:1:500-2000

Western Blot (WB) of anti-RPN1 antibody
Western blot
All lanes: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa
subunit antibody at 2ug/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size: 50kDa
Observed band size: 50kDa
Additional bands at: 20kDa,30kDa
.
anti-RPN1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-RPN1 antibody
Immunohistochemistry of paraffin-embedded human colon cancer using MBS7000935 at dilution of 1:100
anti-RPN1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for RPN1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,569 Da[Similar Products]
NCBI Official Full Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
NCBI Official Synonym Full Names
ribophorin I
NCBI Official Symbol
NCBI Official Synonym Symbols
OST1; RBPH1
  [Similar Products]
NCBI Protein Information
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
UniProt Protein Name
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
UniProt Synonym Protein Names
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; Ribophorin I; RPN-I; Ribophorin-1
UniProt Gene Name
UniProt Synonym Gene Names
RPN-I  [Similar Products]
UniProt Entry Name
RPN1_HUMAN
NCBI Summary for RPN1
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. [provided by RefSeq, Jul 2008]
UniProt Comments for RPN1
RPN1: Essential subunit of N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Belongs to the OST1 family.

Protein type: Transferase; EC 2.4.99.18; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: endoplasmic reticulum membrane; integral to membrane; melanosome; membrane; oligosaccharyl transferase complex; rough endoplasmic reticulum

Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity; protein binding

Biological Process: cellular protein metabolic process; gene expression; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; protein modification process; SRP-dependent cotranslational protein targeting to membrane; translation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-RPN1 antibody
 Reference Product  PubMed Publications
 RPN2 antibody  >16 publications with RPN1 and RPN2
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