NP_001273484.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,268 Da
NCBI Official Full Name
dual specificity protein phosphatase 22 isoform a
NCBI Official Synonym Full Names
dual specificity phosphatase 22
NCBI Official Synonym Symbols
VHX; JKAP; JSP1; MKPX; JSP-1; MKP-x; LMWDSP2; LMW-DSP2 [Similar Products]
NCBI Protein Information
dual specificity protein phosphatase 22
UniProt Protein Name
Dual specificity protein phosphatase 22
UniProt Synonym Protein Names
JNK-stimulatory phosphatase-1; JSP-1; Low molecular weight dual specificity phosphatase 2; LMW-DSP2; Mitogen-activated protein kinase phosphatase x; MAP kinase phosphatase x; MKP-x
UniProt Synonym Gene Names
JSP1; LMWDSP2; MKPX; JSP-1; LMW-DSP2; MAP kinase phosphatase x; MKP-x [Similar Products]
UniProt Entry Name
DUS22_HUMAN
UniProt Comments for DUSP22
DUSP22: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK). Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; EC 3.1.3.16; Apoptosis; EC 3.1.3.48; Protein phosphatase, dual-specificity
Chromosomal Location of Human Ortholog: 6p25.3
Cellular Component: cytoplasm; nucleus
Molecular Function: protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity
Biological Process: cell proliferation; apoptosis; transforming growth factor beta receptor signaling pathway; multicellular organismal development; positive regulation of JNK cascade; negative regulation of transcription from RNA polymerase II promoter; protein amino acid dephosphorylation; regulation of cell proliferation; inactivation of MAPK activity
Research Articles on DUSP22
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Products associated with anti-DUSP22 antibody
Diseases associated with anti-DUSP22 antibody
Organs/Tissues associated with anti-DUSP22 antibody
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