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anti-PROCR antibody :: Rabbit anti-Human Endothelial protein C receptor Polyclonal Antibody

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Catalog # MBS1265009
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
anti-PROCR antibody
Product Name

Endothelial protein C receptor (PROCR), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Endothelial protein C receptor polyclonal Antibody, Biotin conjugated

Product Synonym Names
Activated protein C receptor; Endothelial cell protein C receptor; CD_antigen=CD201; PROCR; EPCR
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600646
3D Structure
ModBase 3D Structure for Q9UNN8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Biotin
Immunogen
Recombinant human Endothelial protein C receptor protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23575 / sc-31264 / sc-31265 / sc-28978
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-PROCR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PROCR antibody
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
Applications Tested/Suitable for anti-PROCR antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for PROCR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,671 Da[Similar Products]
NCBI Official Full Name
endothelial protein C receptor
NCBI Official Synonym Full Names
protein C receptor
NCBI Official Symbol
PROCR  [Similar Products]
NCBI Official Synonym Symbols
CCCA; EPCR; CCD41
  [Similar Products]
NCBI Protein Information
endothelial protein C receptor
UniProt Protein Name
Endothelial protein C receptor
UniProt Synonym Protein Names
Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201
UniProt Gene Name
PROCR  [Similar Products]
UniProt Synonym Gene Names
EPCR; APC receptor  [Similar Products]
UniProt Entry Name
EPCR_HUMAN
NCBI Summary for PROCR
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
UniProt Comments for PROCR
EPCR: a single-pass type I membrane protein. Binds activated protein C (APC), a serine protease that regulates thrombin (IIa) production. Plays a pivotal role in preventing blood coagulation through binding of activated protein C. Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. The binding of APC to EPCR and PAR-1 increases invasion and chemotaxis.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 20q11.2

Cellular Component: cell surface; centrosome; extracellular region; focal adhesion; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: blood coagulation; immune response; leukocyte migration; negative regulation of coagulation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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