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anti-PTGER1 antibody :: Goat EP1 receptor/PTGER1 Polyclonal Antibody

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Catalog # MBS420141
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

EP1 receptor/PTGER1, Polyclonal Antibody

Popular Item
Also Known As

Goat anti-EP1 receptor/PTGER1 Antibody

Product Synonym Names
PTGER1; prostaglandin E receptor 1 (subtype EP1), 42kDa; EP1; PGE receptor, EP1 subtype; prostaglandin E receptor 1, subtype EP1; prostanoid EP1 receptor; PTGER1 antibody; prostaglandin E receptor 1 (subtype EP1); 42kDa antibody; EP1 antibody; PGE receptor; EP1 subtype antibody; prostaglandin E receptor 1; subtype EP1 antibody; prostanoid EP1 receptor antibody; EP1 receptor / PTGER1
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
402
Immunogen Sequence
DSRRRWGAHG PRS
OMIM
176802
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-DSRRRWGAHGPRS, from the internal region of the protein sequence according to NP_000946.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-PTGER1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PTGER1 antibody
Peptide ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-PTGER1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Immunohistochemistry: In paraffin embedded Human Kidney shows membranous staining in the epithelial cells of DCT. Recommended concentration, 1-2ug/ml.

Immunohistochemistry (IHC) of anti-PTGER1 antibody
(2ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
anti-PTGER1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PTGER1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,801 Da
NCBI Official Full Name
prostaglandin E2 receptor EP1 subtype
NCBI Official Synonym Full Names
prostaglandin E receptor 1
NCBI Official Symbol
PTGER1  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
prostaglandin E2 receptor EP1 subtype
UniProt Protein Name
Prostaglandin E2 receptor EP1 subtype
UniProt Synonym Protein Names
Prostanoid EP1 receptor
Protein Family
UniProt Gene Name
PTGER1  [Similar Products]
UniProt Synonym Gene Names
PGE receptor EP1 subtype; PGE2 receptor EP1 subtype  [Similar Products]
UniProt Entry Name
PE2R1_HUMAN
NCBI Summary for PTGER1
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008]
UniProt Comments for PTGER1
PTGER1: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: prostaglandin E receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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