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anti-EPHX2 antibody :: Rabbit anti-Human epoxide hydrolase 2, cytoplasmic Polyclonal Antibody

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Catalog # MBS714479
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-EPHX2 antibody
Product Name

epoxide hydrolase 2, cytoplasmic (EPHX2), Polyclonal Antibody

Also Known As

Rabbit anti-human epoxide hydrolase 2, cytoplasmic polyclonal Antibody

Product Synonym Names
epoxide hydrolase 2; cytoplasmic; EPHX2; CEH; SEH
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
555
OMIM
132811
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Immunogen
Human EPHX2
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-25797 / sc-87099 / sc-87101
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-EPHX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EPHX2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for EPHX2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,626 Da[Similar Products]
NCBI Official Full Name
Epoxide hydrolase 2, cytoplasmic
NCBI Official Synonym Full Names
epoxide hydrolase 2, cytoplasmic
NCBI Official Symbol
EPHX2  [Similar Products]
NCBI Official Synonym Symbols
CEH; SEH
  [Similar Products]
NCBI Protein Information
bifunctional epoxide hydrolase 2; epoxide hydratase; epoxide hydrolase, soluble; epoxide hydrolase 2, cytosolic
UniProt Protein Name
Bifunctional epoxide hydrolase 2
UniProt Synonym Protein Names
Epoxide hydratase; Soluble epoxide hydrolase; SEH
UniProt Gene Name
EPHX2  [Similar Products]
UniProt Synonym Gene Names
CEH; SEH  [Similar Products]
UniProt Entry Name
HYES_HUMAN
NCBI Summary for EPHX2
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
UniProt Comments for EPHX2
EPHX2: Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo- 9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro- 9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy- octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate. Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.

Protein type: Lipid Metabolism - arachidonic acid; EC 3.3.2.10; EC 3.1.3.76; Hydrolase

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: cytoplasm; peroxisome; cytosol

Molecular Function: toxin binding; protein homodimerization activity; lipid-phosphate phosphatase activity; epoxide hydrolase activity; phosphoric monoester hydrolase activity; magnesium ion binding; lipid phosphatase activity; receptor binding

Biological Process: cellular calcium ion homeostasis; cholesterol homeostasis; dephosphorylation; response to toxin; regulation of blood pressure; xenobiotic metabolic process; arachidonic acid metabolic process; epoxygenase P450 pathway; stilbene catabolic process; positive regulation of vasodilation; drug metabolic process; inflammatory response; phospholipid dephosphorylation

Disease: Hypercholesterolemia, Familial
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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