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anti-F2 antibody :: Rabbit anti-Human F2 Polyclonal Antibody

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Catalog # MBS1499853
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

F2, Polyclonal Antibody

Popular Item
Full Product Name

F2 Antibody

Product Synonym Names
Prothrombin (EC:3.4.21.5); F2; Coagulation factor II; Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
176930
3D Structure
ModBase 3D Structure for P00734
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Prothrombin protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23328 / sc-23352 / sc-23348 / sc-23327 / sc-23337 / sc-16972 / sc-33769
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-F2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-F2 antibody
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
Applications Tested/Suitable for anti-F2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Immunofluorescence (IF) of anti-F2 antibody
Immunofluorescent analysis of Hela cells using MBS1499853 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-F2 antibody Immunofluorescence (IF) image
Western Blot (WB) of anti-F2 antibody
Western Blot
Positive WB detected in:A549 whole cell lysate
All lanes: F2 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71 kDa
Observed band size: 71 kDa

anti-F2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for F2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
70,037 Da
NCBI Official Full Name
prothrombin isoform 1 preproprotein
NCBI Official Synonym Full Names
coagulation factor II, thrombin
NCBI Official Symbol
NCBI Official Synonym Symbols
PT; THPH1; RPRGL2
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NCBI Protein Information
prothrombin
UniProt Protein Name
Prothrombin
UniProt Synonym Protein Names
Coagulation factor II
Protein Family
UniProt Gene Name
UniProt Entry Name
THRB_HUMAN
NCBI Summary for F2
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
UniProt Comments for F2
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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