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anti-FAM109A antibody :: Rabbit anti-Human FAM109A Polyclonal Antibody

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Catalog # MBS9207877
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Product Name

FAM109A, Polyclonal Antibody

Popular Item
Also Known As

FAM109A Antibody (N-term)

Product Synonym Names
Sesquipedalian-1; Ses1; 27 kDa inositol polyphosphate phosphatase-interacting protein A; IPIP27A; FAM109A
Antibody/Peptide Pairs
FAM109A peptide (MBS9218897) is used for blocking the activity of FAM109A antibody (MBS9207877)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
3-31
Immunogen Sequence Length
262
3D Structure
ModBase 3D Structure for Q8N4B1
Clonality
Polyclonal
Isotype
Rabbit Ig
Clone Number
RB32032
Host
Rabbit
Species Reactivity
Human
Specificity
This FAM109A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-31 amino acids from the N-terminal region of human FAM109A.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
Cellular Location
Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-FAM109A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FAM109A antibody
This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants.
Applications Tested/Suitable for anti-FAM109A antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-FAM109A antibody
WB~~1:1000
IHC-P~~1:10~50

Western Blot (WB) of anti-FAM109A antibody
FAM109A Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the FAM109A antibody detected the FAM109A protein (arrow).
anti-FAM109A antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-FAM109A antibody
FAM109A Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FAM109A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-FAM109A antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for FAM109A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27215
NCBI Official Full Name
sesquipedalian-1 isoform 1
NCBI Official Synonym Full Names
family with sequence similarity 109, member A
NCBI Official Symbol
FAM109A  [Similar Products]
NCBI Official Synonym Symbols
SES1; IPIP27A
  [Similar Products]
NCBI Protein Information
sesquipedalian-1
UniProt Protein Name
Sesquipedalian-1
UniProt Synonym Protein Names
27 kDa inositol polyphosphate phosphatase-interacting protein A; IPIP27A
Protein Family
UniProt Gene Name
FAM109A  [Similar Products]
UniProt Synonym Gene Names
Ses1; IPIP27A  [Similar Products]
UniProt Entry Name
SESQ1_HUMAN
NCBI Summary for FAM109A
This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Comments for FAM109A
FAM109A: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. Belongs to the sesquipedalian family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 12q24.12

Cellular Component: recycling endosome; clathrin-coated vesicle; early endosome; trans-Golgi network

Molecular Function: protein binding; protein homodimerization activity

Biological Process: receptor recycling; endosome organization and biogenesis; retrograde transport, endosome to Golgi
Product References and Citations for anti-FAM109A antibody
Swan, L.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(8):3511-3516(2010)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-FAM109A antibody
Diseases associated with anti-FAM109A antibody
Organs/Tissues associated with anti-FAM109A antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with FAM109A and Kidney
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