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anti-FCRL4 antibody :: Rabbit anti-Human FCRL4 Polyclonal Antibody

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Catalog # MBS6000748
Unit / Price
  0.2 mL  /  $550 +1 FREE 8GB USB
Product Name

FCRL4, Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-Human FCRL4, CT (FCRL4, FCRH4, IFGP2, IRTA1, Fc receptor-like protein 4, Fc receptor homolog 4, IFGP family protein 2, Immune receptor translocation-associated protein 1, CD307d)

Product Synonym Names
Anti -FCRL4, CT (FCRL4, FCRH4, IFGP2, IRTA1, Fc receptor-like protein 4, Fc receptor homolog 4, IFGP family protein 2, Immune receptor translocation-associated protein 1, CD307d)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 1; NC_000001.10 (157543539..157567870, complement). Location: 1q21
OMIM
605876
3D Structure
ModBase 3D Structure for Q96PJ5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Recognizes Human FCRL4
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration
0.5 mg/ml (lot specific)
Immunogen
KLH conjugated synthetic peptide mapping to a fragment of residues within amino acids aa480-507 in the C-terminal region of human FCRL4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-FCRL4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FCRL4 antibody
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
Product Categories/Family for anti-FCRL4 antibody
Applications Tested/Suitable for anti-FCRL4 antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-FCRL4 antibody
Dilution:
Western Blot: 1:2000
Flow Cytometry: 1:10-50
Optimal dilutions to be determined by the researcher

Western Blot of anti-FCRL4 antibody
Western Blot analysis in Ramos cell line lysates (35ug/lane). FCRL4 (arrow) was detected using the purified Pab
anti-FCRL4 antibody Western Blot (WB) image
Flow Cytometric of anti-FCRL4 antibody
Flow Cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
anti-FCRL4 antibody Flow Cytometric image
NCBI/Uniprot data below describe general gene information for FCRL4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,224 Da[Similar Products]
NCBI Official Full Name
Fc receptor-like protein 4
NCBI Official Synonym Full Names
Fc receptor-like 4
NCBI Official Symbol
FCRL4  [Similar Products]
NCBI Official Synonym Symbols
FCRH4; IGFP2; IRTA1; CD307d
  [Similar Products]
NCBI Protein Information
Fc receptor-like protein 4; hIFGP2; fcR-like protein 4; IFGP family protein 2; fc receptor homolog 4; immunoglobulin superfamily Fc receptor, gp42; immune receptor translocation-associated protein 1; immunoglobulin superfamily receptor translocation associated 1
UniProt Protein Name
Fc receptor-like protein 4
UniProt Synonym Protein Names
Fc receptor homolog 4; FcRH4; IFGP family protein 2; hIFGP2; Immune receptor translocation-associated protein 1
Protein Family
UniProt Gene Name
FCRL4  [Similar Products]
UniProt Synonym Gene Names
FCRH4; IFGP2; IRTA1; FcR-like protein 4; FcRL4; FcRH4; hIFGP2  [Similar Products]
UniProt Entry Name
FCRL4_HUMAN
NCBI Summary for FCRL4
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]
UniProt Comments for FCRL4
FCRL4: May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response. A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2). A chromosomal aberration involving FCRL4 is found in multiple myeloma (MM). Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: plasma membrane; integral to membrane

Molecular Function: protein binding

Biological Process: immune system process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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