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anti-FcRn antibody :: Rabbit anti-Human FcRn Polyclonal Antibody

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Catalog # MBS769295
Unit / Price
  0.1 mg  /  $320 +1 FREE 8GB USB
Product Name

FcRn, Polyclonal Antibody

Popular Item
Full Product Name

FcRn-Specific Rabbit Polyclonal

Product Synonym Names
Alpha chain, FCGRT, FCRN, Neonatal Fc receptor
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS769295 Technical Datasheet
3D Structure
ModBase 3D Structure for P55899
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Human; other species are not tested.
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Immunogen
Fc fragment of IgG, receptor, transporter, alpha
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-FcRn antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FcRn antibody
The neonatal Fc receptor for IgG (FcRn) is a membrane-associated receptor which acts as a key determinant of IgG homeostasis. FcRn is similar in structure to major histocompatibility class I molecules. It is a heterodimer composed of a alpha chain associated with Beta2-microglobulin. FcRn transfers IgG from the mother to the fetus across the placenta and the proximal small intestine. In addition, throughout life, FcRn protects IgG from degradation and thus regulates the serum half-life of IgG (PMID: 17703228)
Applications Tested/Suitable for anti-FcRn antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-FcRn antibody
WB: 1:200-1:1000

Western Blot of anti-FcRn antibody
Human placenta tissue were subjected to SDS-PAGE followed by western blot (FCGRT-Specific antibody) at dilution of 1:300
anti-FcRn antibody Western Blot (WB) image
SDS-PAGE of anti-FcRn antibody
Immunohistochemical of paraffin-embedded human brain using MBS7603167(PTPN18 antibody) at dilution of 1: 100
anti-FcRn antibody SDS-PAGE image
NCBI/Uniprot data below describe general gene information for FcRn. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
Molecular Weight
40kDa,observed 35kDa
NCBI Official Full Name
FcRn, partial
UniProt Protein Name
FcRn
UniProt Synonym Protein Names
FcRn
UniProt Entry Name
A9QU27_BUBBU
UniProt Comments for FcRn
FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: plasma membrane

Molecular Function: antigen binding; beta-2-microglobulin binding; IgG binding; IgG receptor activity; peptide antigen binding

Biological Process: antigen processing and presentation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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