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anti-FCN1 antibody :: Rabbit Ficolin 1 (FCN1) Polyclonal Antibody

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Catalog # MBS2017851 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
Scan QR to view Datasheet
  0.01 mg  /  $115 +1 FREE 8GB USB
  0.02 mg  /  $135 +1 FREE 8GB USB
  0.05 mg  /  $190 +1 FREE 8GB USB
  0.1 mg  /  $245 +1 FREE 8GB USB
  0.2 mg  /  $365 +1 FREE 8GB USB
  1 mg  /  $865 +1 FREE 8GB USB
anti-FCN1 antibody
Product Name

Ficolin 1 (FCN1), Polyclonal Antibody

Popular Item
Full Product Name

FITC-linked Antibody to Ficolin 1 (FCN1)

Matching Pairs
Unconjugated Antibody: Ficolin 1 (FCN1) (MBS2015772)
FITC Conjugated Antibody: Ficolin 1 (FCN1) (MBS2017851)
Matching Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2017851 Technical Datasheet
Chromosome Location
Chromosome: 9; NC_000009.11 (137797711..137809849, complement). Location: 9q34
OMIM
601252
3D Structure
ModBase 3D Structure for O00602
Clonality
Polyclonal
Host
Rabbit
Purity/Purification
Antigen-specific Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH 7.4 containing 1%BSA, 0.02% NaN3, 50% glycerol.
Concentration
0.31 mg/ml (lot specific)
Organism Species
Homo sapiens (Human)
Source
Antibody labeling
Label
FITC
Traits
Liquid
Immunogen
Recombinant FCN1 (Asp45~Thr249) expressed in E.coli.
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20oC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-FCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-FCN1 antibody
Applications Tested/Suitable for anti-FCN1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF).
Application Notes for anti-FCN1 antibody
Western blotting: 0.5-2 ug/mL;1:150-620
Immunohistochemistry: 5-20 ug/mL;1:150-620
Immunocytochemistry: 5-20 ug/mL;1:150-620

Optimal working dilutions must be determined by end user
NCBI/Uniprot data below describe general gene information for FCN1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ficolin-1
NCBI Official Synonym Full Names
ficolin (collagen/fibrinogen domain containing) 1
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
ficolin-1; M-ficolin; ficolin-A; ficolin-alpha; collagen/fibrinogen domain-containing protein 1; ficolin (collagen/fibrinogen domain-containing) 1
UniProt Protein Name
Ficolin-1
UniProt Synonym Protein Names
Collagen/fibrinogen domain-containing protein 1; Ficolin-A; Ficolin-alpha; M-ficolin
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
FCN1_HUMAN
NCBI Summary for FCN1
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]
UniProt Comments for FCN1
FCN1: Complement-activating lectin and pattern recognition receptor. Binds GlcNAc. Binds preferentially to 9-O-acetylated 2- 6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. Belongs to the ficolin lectin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: collagen; extrinsic to external side of plasma membrane; extracellular region

Molecular Function: protein binding; G-protein-coupled receptor binding; metal ion binding; carbohydrate binding; pattern recognition receptor activity; sialic acid binding

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of virion penetration into host cell; cell surface pattern recognition receptor signaling pathway; innate immune response; complement activation, lectin pathway; recognition of apoptotic cell; complement activation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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