NP_001005738.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,964 Da
NCBI Official Full Name
N-formyl peptide receptor 2
NCBI Official Synonym Full Names
formyl peptide receptor 2
NCBI Official Synonym Symbols
ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II [Similar Products]
NCBI Protein Information
N-formyl peptide receptor 2
UniProt Protein Name
N-formyl peptide receptor 2
UniProt Synonym Protein Names
FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
UniProt Synonym Gene Names
UniProt Entry Name
FPR2_HUMAN
UniProt Comments for FPR2
FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.
Protein type: Motility/polarity/chemotaxis; GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19q13.3-q13.4
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity
Biological Process: cell adhesion; cell motility; chemotaxis; G-protein coupled receptor protein signaling pathway; inflammatory response
Research Articles on FPR2
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Pathways associated with anti-FPR2 antibody
Diseases associated with anti-FPR2 antibody
Organs/Tissues associated with anti-FPR2 antibody
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