• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-GABRG2 antibody :: Rabbit anti-Human GABA Receptor A, gamma2 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS627298
Unit / Price
Scan QR to view Datasheet
  0.1 mL  /  $745 +1 FREE 8GB USB
anti-GABRG2 antibody
Product Name

GABA Receptor A, gamma2 (GABRG2), Polyclonal Antibody

Full Product Name

Anti-GABA Receptor A, gamma2 (Gamma-aminobutyric Acid Receptor Type A gamma Subunit, GABRA)

Product Synonym Names
Gamma-aminobutyric Acid Receptor Type A gamma Subunit; GABRA
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 5; NC_000005.9 (161494648..161582545). Location: 5q34
OMIM
137164
3D Structure
ModBase 3D Structure for P18507
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
Recognizes the human GAG2 protein.
Purity/Purification
Affinity Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, before the addition of glycerol to 40%.
Concentration
~1mg/ml (lot specific)
Immunogen
Recombinant GAG2 fragment 189-299aa. Location: ~Extracellular domain.
Source Information
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Temperature: Blue Ice
Other Notes
Small volumes of anti-GABRG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GABRG2 antibody
GABA (g-amino butyric acid) is the most abundant neurotransmitter in mammalian brain. GABA exerts its effects through ionotropic ligand-gated GABAA, GABAC and GABAB receptors (GABABRs). A family of GABA-A receptors subtypes exists, which are generated by alternative splicing of alpha 1-6, beta 1-4, gamma 1-4, delta, epsilon, pie, theta, and rho1-3 to form a heteromeric (pentameric) protein complexes. Various GABA-A subunits show distinct patterns of temporal and spatial expression that may imply its tissue specific physiological role (1). GABA A (GAA) receptor proteins (450-627 aa) are characterized by the presence of a cleavable signal peptide, a large extracellular N-terminus, 3 TM (transmembrane) domains, a large cytoplasmic domain followed by TM4 and C-terminal extracellular domain. The regions between TM3-4 and the large cytoplasmic loop are least conserved among various GAA subunits, which may confer subunit specific functionality. GAA genes are distributed as clusters throughout the human genome (chromosomes 4, 5, 15, and X; delta subunit on chromosome 1). GAA in the brain are the targets of many clinically important drugs.
Product Categories/Family for anti-GABRG2 antibody
Applications Tested/Suitable for anti-GABRG2 antibody
ELISA; Western Blot
Application Notes for anti-GABRG2 antibody
Western Blot: 1-2ug/ml using ECL technique.
ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml.
NCBI/Uniprot data below describe general gene information for GABRG2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,162 Da[Similar Products]
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit gamma-2 isoform 1
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) A receptor, gamma 2
NCBI Official Symbol
GABRG2  [Similar Products]
NCBI Official Synonym Symbols
CAE2; ECA2; GEFSP3
  [Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit gamma-2; OTTHUMP00000160873; OTTHUMP00000160874; OTTHUMP00000224398; OTTHUMP00000224400; GABA(A) receptor subunit gamma-2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit gamma-2
UniProt Synonym Protein Names
GABA(A) receptor subunit gamma-2
UniProt Gene Name
GABRG2  [Similar Products]
UniProt Entry Name
GBRG2_HUMAN
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-GABRG2 antibody
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000